(Z)-4-chloro-7-(dimethylamino)-3-(2-(quinolin-4-yl)vinyl)-2H-chromen-2-one | 1360146-08-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: (Z)-4-chloro-7-(dimethylamino)-3-(2-(quinolin-4-yl)vinyl)-2H-chromen-2-one
• CAS: 1360146-08-2
• 化学式: C₂₂H₁₇ClN₂O₂
• 分子量: 376.842
• InChiKey: SAQLDFFMXWOBLO-CLFYSBASSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.23
• 重原子数：
  27.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  46.34
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  (E)-4-chloro-7-(dimethylamino)-3-(2-(quinolin-4-yl)vinyl)-2H-chromen-2-one 以 氘代氯仿 为溶剂， 反应 1.0h， 生成 (Z)-4-chloro-7-(dimethylamino)-3-(2-(quinolin-4-yl)vinyl)-2H-chromen-2-one
  参考文献：
  名称：

  One-Pot Synthesis of Pyranocoumarins via Microwave-Assisted Pseudo Multicomponent Reactions and Their Molecular Switching Properties

  摘要：

  Two new pyranocoumarins were synthesized via one-pot, microwave-assisted pseudo multicomponent condensations of coumarin and 4-methylquinoline to investigate their molecular switching properties. Both are light-sensitive and have a distinct change of color upon UV irradiation. The reaction can be reverted by treating the photogenerated products with imidazoline-functionalized magnetic nanoparticles, which can be swiftly recycled with an external permanent magnet.

  DOI：

  10.1021/ol203229z