L-Glutamic acid, ester with D-glucose | 82643-14-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: L-Glutamic acid, ester with D-glucose
• 英文别名: (2S)-2-aminopentanedioic acid;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
• CAS: 82643-14-9
• 化学式: C11H21NO10
• 分子量: 327.28
• InChiKey: SPLIXMVCDRBRKV-BCLLBKCYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.12
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  219
• 氢给体数：
  8
• 氢受体数：
  11

文献信息

• IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES
  申请人：Schmitt-Willich Heribert

  公开号：US20130034497A1

  公开（公告）日：2013-02-07

  This invention relates to derivatives of Iodine-labeled homoglutamic acids and glutamic acids and their analogues suitable for labeling or already labeled by Iodine, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging or radiotherapy.

  本发明涉及碘标记的同型谷氨酸和谷氨酸及其类似物的衍生物，适用于标记或已经被碘标记，制备这种化合物的方法，包含这种化合物的组合物，包含这种化合物或组合物的试剂盒以及这种化合物、组合物或试剂盒用于诊断成像或放射治疗的用途。
• Method of bod measurement and apparatus thereof
  申请人：Kao Corporation

  公开号：EP0369490A2

  公开（公告）日：1990-05-23

  In a method of measurement of BOD value of test solution by comparing dissolved oxygen decrement ΔDO of the test solution with dissolved oxygen decrement of standard solution sterilized test solution is used as the standard solution. Apparatus for conducting the above method is also disclosed. BOD value is calculated using the measured ΔDO by a relation between 1/BOD and 1/ΔDO. The apparatus comprises a column for contacting solution with the microorganism, oxygen electrodes disposed before and after the column for measuring the dissolved oxygen value, whereby in an inject condition, the test solution is fed to the oxygen electrode before the column and in the lead condition the test solution is fed to the oxygen electrode after the column, so that ΔDO can be measured by the two oxygen electrodes. In the apparatus, the inject condition and the load condition are changed by solenoid valves or rotary valves.

  在一种通过比较试验溶液的溶解氧减少量 ΔDO 和标准溶液的溶解氧减少量来测量试验溶液生化需氧量值的方法中，灭菌试验溶液被用作标准溶液。还公开了用于执行上述方法的仪器。 根据 1/BOD 和 1/ΔDO 之间的关系，利用测得的ΔDO 计算 BOD 值。 该装置包括一个用于使溶液与微生物接触的色谱柱，以及设置在色谱柱前后用于测量溶解氧值的氧电极，其中，在注入条件下，将测试溶液注入色谱柱前的氧电极，而在导入条件下，将测试溶液注入色谱柱后的氧电极，这样就可以通过两个氧电极测量ΔDO。 在仪器中，注入条件和负载条件由电磁阀或旋转阀改变。
• 5-Aminolevulinic acid producing microorganism, and process for producing it
  申请人：COSMO RESEARCH INSTITUTE

  公开号：EP0718405A2

  公开（公告）日：1996-06-26

  A microorganism that produces 5-aminolevulinic acid, wherein the microorganism has a 5-aminolevulinic acid dehydratase variant having a reduced inhibitor constant for a 5-aminolevulinic acid dehydratase inhibitor. A microorganism that produces 5-aminolevulinic acid, wherein the microorganism is a photosynthetic bacterium that produces 5-aminolevulinic acid without light irradiation. A process for producing 5-aminolevulinic acid comprising the step of culturing a microorganism that produces 5-aminolevulinic acid in a culture medium under at least one condition selected from the group consisting of (a) less than 1 ppm of dissolved oxygen concentration in the culture medium, (b) from -180 to 50 mV of oxidation-reduction potential in the culture medium, and ( c ) from 5×10⁻⁹ to (KrM - 2×10⁻⁸) (mol of O₂/mℓ·min·cell) of cellular respiration rate, wherein KrM represents the maximum cellular respiration rate when oxygen is supplied in an excess quantity.

  一种生产 5-氨基乙酰丙酸的微生物，其中该微生物具有 5-氨基乙酰丙酸脱水酶变体，该变体对 5-氨基乙酰丙酸脱水酶抑制剂的抑制常数降低。一种可生产 5-氨基乙酰丙酸的微生物，其中所述微生物是一种光合细菌，可在无光照的情况下生产 5-氨基乙酰丙酸。一种生产 5-氨基乙酰丙酸的工艺，包括以下步骤：在培养基中培养产生 5-氨基乙酰丙酸的微生物，培养基的至少一种条件选自以下一组 (a) 培养基中溶解氧浓度低于 1 ppm、(b) 培养基中的氧化还原电位为-180 至 50 mV，以及 (c) 细胞呼吸速率为 5×10-⁹ 至 (KrM - 2×10-⁸) (mol of O₂/mℓ-min-cell) 之间，其中 KrM 代表过量供氧时的最大细胞呼吸速率。
• 5-Aminolevulinic acid producing microorganism and process for producing 5-aminolevulinic acid
  申请人：COSMO RESEARCH INSTITUTE

  公开号：EP1041154A1

  公开（公告）日：2000-10-04

  A microorganism that produces 5-aminolevulinic acid, wherein the microorganism has a 5-aminolevulinic acid dehydratase variant having a reduced inhibitor constant for a 5-aminolevulinic acid dehydratase inhibitor. A microorganism that produces 5-aminolevulinic acid, wherein the microorganism is a photosynthetic bacterium that produces 5-aminolevulinic acid without light irradiation. A process for producing 5-aminolevulinic acid comprising the step of culturing a microorganism that produces 5-aminolevulinic acid in a culture medium under at least one condition selected from the group consisting of (a) less than 1 ppm of dissolved oxygen concentration in the culture medium, (b) from -180 to 50 mV of oxidation-reduction potential in the culture medium, and (c) from 5×10-9 to (KrM - 2×10-8) (mol of O2/mℓ·min·cell) of cellular respiration rate, wherein KrM represents the maximum cellular respiration rate when oxygen is supplied in an excess quantity.

  一种生产 5-氨基乙酰丙酸的微生物，其中该微生物具有 5-氨基乙酰丙酸脱水酶变体，该变体对 5-氨基乙酰丙酸脱水酶抑制剂的抑制常数降低。一种可生产 5-氨基乙酰丙酸的微生物，其中所述微生物是一种光合细菌，可在无光照的情况下生产 5-氨基乙酰丙酸。一种生产 5-氨基乙酰丙酸的工艺，包括以下步骤：在培养基中培养产生 5-氨基乙酰丙酸的微生物，培养基的至少一种条件选自以下一组 (a) 培养基中溶解氧浓度低于 1 ppm、(c) 细胞呼吸速率为 5×10-9 至 (KrM - 2×10-8)（mol of O2/mℓ-min-cell），其中 KrM 代表过量供氧时的最大细胞呼吸速率。
• Process for the preparation of cell beads BOD sensor useful for instant BOD estimation
  申请人：——

  公开号：US20030036186A1

  公开（公告）日：2003-02-20

  Immobilized cell beads incorporating formulated microbial consortium comprising a synergistic mixture of the following bacterial strains namely, Enterobacter sakazaki, Pseudomonas aeruginosa and Aeromonas sobria selected from the following isolated bacterial strains namely, Yersinia enterocolitica, Aeromonas sobria, Klebsiella pneumoniae, Serratia liquefaciens, Enterobacter sakazaki, Citrobacter amalonaticus, Pseudomonas fluorescens, Pseudomonas aeruginosa, Enterobacter cloaca, Acinetobacter calcoaceticus are prepared, the formulated microbial consortium is immobilized in an appropriate immobilizing agent resulting in the formation of beads and the beads are used for instant BOD estimation using an electronic device and the formulated cell beads are reusable and are capable of assimilating most of the organic matter present in varied industrial effluents.

  固定化细胞珠，其中含有由下列细菌菌株协同混合物组成的配制微生物菌群，即 阪崎肠杆菌、铜绿假单胞菌 和 褐藻气单胞菌 从下列分离细菌菌株中选出的菌株，即 小肠结肠炎耶尔森氏菌、索布里亚气单胞菌、肺炎克雷伯氏菌、液化沙雷氏菌、坂崎肠杆菌、氨丙酸柠檬酸杆菌、荧光假单胞菌、铜绿假单胞菌、泄殖腔肠杆菌、醋酸钙不动杆菌。 配制好的细胞珠可重复使用，并能同化各种工业废水中的大部分有机物。