| 213595-57-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• CAS: 213595-57-4
• 化学式: C₅₂H₃₆Cl₄O₈
• 分子量: 930.665
• InChiKey: BKKTYJXPGMGTKG-QEZAZGETSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.98
• 重原子数：
  64.0
• 可旋转键数：
  4.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  161.84
• 氢给体数：
  8.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  4-氯苯甲醛 、 间苯二酚 在 iron(II,III) oxide 作用下， 反应 0.55h， 以90%的产率得到
  参考文献：
  名称：

  Fe3O4纳米颗粒：一种功能强大且可磁回收的催化剂，用于合成新型杯[4]间苯二芳烃

  摘要：

  摘要通过在无溶剂条件下催化量的Fe 3 O 4纳米粒子存在下，间苯二酚与不同的芳族醛缩合，可以轻松合成新颖的已知杯[4]间苯二芳烃衍生物。实验条件已经过全面优化和建立，可以显着提高速率并获得良好至极佳的产量。在温和的反应条件下，无需使用任何有毒的有机溶剂，即可安全地进行反应。通过粉末X射线衍射（XRD），透射电子显微镜（TEM）和FT-IR光谱对Fe 3 O 4纳米颗粒进行了表征。

  DOI：

  10.1016/j.cclet.2011.11.005

文献信息

• A Green and Highly Efficient Solvent-free Synthesis of Novel Calicx[4]resorcinarene Derivatives Using Tungstate Sulfuric Acid
  作者：Bahador Karami、Saeed Khodabakhshi、Niloofar Safikhani、Afsaneh Arami

  DOI：10.5012/bkcs.2012.33.1.123

  日期：2012.1.20

  facile and simple procedure for the synthesis of novel and known calix[4]resorcinarene derivatives were developed via a reaction of arylaldehydes with resorcinol in the presence of catalytic amounts of tungstate sulfuric acid (TSA) under solvent-free conditions. This eco-friendly method has many appealing attributes, such as excellent yields, short reactions times, use of safe and recoverable catalyst

  通过芳基醛与间苯二酚在催化量的钨酸盐硫酸 (TSA) 存在下在无溶剂条件下的反应，开发了一种用于合成新型和已知的杯 [4] 间苯二酚衍生物的简便方法。这种环保方法具有许多吸引人的特点，例如产率高、反应时间短、使用安全且可回收的催化剂以及简单的后处理程序。通过粉末 X 射线衍射 (XRD)、X 射线荧光 (XRF) 和 FTIR 光谱对 TSA 进行表征。
• A reactive and environmentally friendly protocol for expeditious synthesis of various resorcinarenes using zinc hydrogen sulfate
  作者：Arash Mouradzadegun、Mohammad Reza Ganjali、Neda Kheirandish、Fatemeh Abadast

  DOI：10.1080/10610278.2019.1598557

  日期：2019.6.3

  In this work, for the first time, metal hydrogen phosphates and sulfates have been studied as effective solid acid catalysts for the condensation of resorcinol with aromatic and aliphatic aldehydes to give tetrameric cyclic products, resorcinarenes, which have major roles in biological and industrial activities. This catalyst has several advantages, it is non-toxic, thermally and mechanically stable, inexpensive and highly resistant against organic solvents. It increases the reaction rate about six fold and makes this method an attractive alternative to the existing methods for resorcinarene formation. Interestingly, the present catalyst exhibited a high turnover number (TON) and turnover frequency (TOF) which were even comparable with that of HCl.[GRAPHICS].