N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine | 154437-05-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine
• CAS: 154437-05-5
• 化学式: C₁₁H₁₂N₂Se
• 分子量: 251.19
• InChiKey: FAWACSAMXFCPIU-UHFFFAOYSA-N

物化性质

• 熔点：
  112 °C
• 沸点：
  347.8±35.0 °C(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.87
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  16.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,4-dinitrobenzene-1-diazonium tertafluoroborate 、 N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine 以 二甲基亚砜 为溶剂， 以15%的产率得到2-(N,N-dimethylamino)-5-(2,4-dinitrophenylazo)-4-phenylselenazole
  参考文献：
  名称：

  Preparation and UV/Vis Spectroscopic Characterization of N,N-Disubstituted 2-Amino-5-arylazoselenazoles and Some of Their Carbocyclic and Heterocyclic Analogues

  摘要：

  By coupling of aryldiazonium salts 5 with N,N-disubstituted 2-amino-5H-selenazoles 4 deeply coloured 5-arylazo-substituted 2-amino-selenazoles 6a-6l have been prepared and their solvatochromic properties deter-mined by means of UV/Vis spectroscopy, and compared with the ones of several other arylazosubstituted N,N'-dialkylanilines 7a-7d, 2-(N,N-dialkylamino)-thiophenes 8a-8e, and 2-(N,N-dialkylamino)-thiazoles 9a-9c.

  DOI：

  10.1002/(sici)1521-3897(200002)342:2<169::aid-prac169>3.3.co;2-y
• 作为产物：
  描述：

  1,1-二甲基-2-硒脲 、 2,2-二溴-1-苯乙酮 以 水 为溶剂， 生成 N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine
  参考文献：
  名称：

  A tandem one-pot aqueous phase synthesis of thiazoles/selenazoles

  摘要：

  The first ever tandem one-pot synthetic protocol for the synthesis of thiazoles/selenazoles from alkynes via the formation of 2,2-dibromo-1-phenylethanone is reported. The reaction is catalyzed by beta-cyclodextrin in aqueous medium and resulted in good yields. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.04.097

文献信息

• PREPARATION AND CHARACTERISATION OF <i>N,N</i>-DISUBSTITUTED 2-AMINO-SELENAZOLES
  作者：Dietmar Keil、Horst Hartmann

  DOI：10.1080/10426509908031628

  日期：1999.9.1

  Abstract As a result of checking suited methods for preparing N,N-disubstituted 2-amino-selenazoles 14 as a nearly unknown class of highly reactive selenazoles a simple route starting from N,N-disubstituted selenoureas 12 has been elaborated and used for the synthesis of a series of these compounds. The necessary selenium-containing starting compounds 12 are available from N,N-disubstituted cyanamides

  摘要 作为一种几乎未知的高反应性硒唑类 N,N-二取代 2-氨基硒唑 14 制备方法的结果，已经制定了一条从 N,N-二取代硒脲 12 开始的简单路线并用于合成一系列这些化合物。必要的含硒起始化合物12可得自N，N-二取代的氰胺18和硒化氢。