Methyl 5-amino-2,4-dimethoxy-3-pyridinecarboxylate | 442903-29-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Methyl 5-amino-2,4-dimethoxy-3-pyridinecarboxylate
• 英文别名: methyl 5-amino-2,4-dimethoxypyridine-3-carboxylate
• CAS: 442903-29-9
• 化学式: C₉H₁₂N₂O₄
• 分子量: 212.2
• InChiKey: JJWXXOGTFITBGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  83.7
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• 1-(2-Methoxybenzyl)-3-benzhydrylpiperazines as tachykinin anatgonists
  申请人：——

  公开号：US20040220403A1

  公开（公告）日：2004-11-04

  A compound of the formula (I): wherein in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 are each as defined in the description, or a salt thereof. The object compound of the present invention has pharmacological activities such as Tachykinin antagonism and is useful for manufacture of a medicament for treating or preventing Tachykinin-mediated diseases. 1 2

  公式（I）的化合物：其中R1，R2，R3，R4，R5，R6，R7，R8，R9，R10和R11分别如描述中所定义，或其盐。本发明的目标化合物具有Tachykinin拮抗等药理活性，并可用于制备治疗或预防Tachykinin介导疾病的药物。
• 1-(2-METHOXYBENZYL)-3-BENZHYDRYLPIPERAZINES AS TACHYKININ ANTAGONISTS
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP1368343A1

  公开（公告）日：2003-12-10
• [EN] 1-(2-METHOXYBENZYL)-3-BENZHYDRYLPIPERAZINES AS TACHYKININ ANTAGONISTS<br/>[FR] 1-(2-METHOXYBENZYL)-3-BENZHYDRYLPIPERAZINES UTILISEES COMME ANTAGONISTES DE LA TACHYKININE
  申请人：FUJISAWA PHARMACEUTICAL CO

  公开号：WO2002055518A1

  公开（公告）日：2002-07-18

  A compound of the formula (I): wherein in which R?1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11¿ are each as defined in the description, or a salt thereof. The object compound of the present invention has pharmacological activities such as Tachykinin antagonism, and is useful for manufacture of a medicament for treating or preventing Tachykinin-mediated diseases.