7-[3-(3,4-bis-hydroxymethylbenzyloxy)phenyl]-3-ethyl-7-methyloctan-3-ol | 268231-90-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 7-[3-(3,4-bis-hydroxymethylbenzyloxy)phenyl]-3-ethyl-7-methyloctan-3-ol
• 英文别名: 7-[3-[[3,4-Bis(hydroxymethyl)phenyl]methoxy]phenyl]-3-ethyl-7-methyloctan-3-ol
• CAS: 268231-90-9
• 化学式: C₂₆H₃₈O₄
• 分子量: 414.585
• InChiKey: AHNDYUYEYKZUAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  30
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  69.9
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Composition in the form of a spray comprising calcitriol
  申请人：GALDERMA RESEARCH & DEVELOPMENT

  公开号：EP1952808A2

  公开（公告）日：2008-08-06

  The invention relates to a composition in the form of a spray comprising a pharmaceutical active agent, at least one volatile silicone and a nonvolatile oily phase in a physiologically acceptable medium, to the process for preparing it and to its use in cosmetics and in dermatology.

  本发明涉及一种喷雾形式的组合物，该组合物包含一种药物活性剂、至少一种挥发性硅氧烷和一种非挥发性油性相，并置于一种生理上可接受的介质中，本发明还涉及该组合物的制备工艺及其在化妆品和皮肤病学中的用途。
• ANALOGUES DE LA VITAMINE D
  申请人：Galderma Research & Development, S.N.C.

  公开号：EP1124779A1

  公开（公告）日：2001-08-22
• SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES
  申请人：GALDERMA RESEARCH & DEVELOPMENT

  公开号：EP1686972B1

  公开（公告）日：2008-03-12
• Pharmaceutical spray compositions comprising a bioactive agent, at least one volatile silicone and a non-volatile oily phase
  申请人：Pitre Franck

  公开号：US20070041910A1

  公开（公告）日：2007-02-22

  Sprayable pharmaceutical compositions suited for improved transdermal penetration contain a) at least one bioactive agent, notably at least one derivative of vitamin D, (b) at least one volatile silicone and c) a non-volatile oily phase, formulated into d) a pharmaceutically acceptable vehicle therefor.
• Anhydrous pharmaceutical composition associating a siliconated agent and solubilised active principle
  申请人：Mallard Claire

  公开号：US20070135379A1

  公开（公告）日：2007-06-14

  The invention relates to an anhydrous pharmaceutical composition associating at least one type of active principle and one type of siliconated agent which comprises at least one type of organopolysiloxane elastomer, wherein said active principle is embodied in the solubilised form thereof in said composition.