N~1~-(2-Aminoethyl)-N~2~-[(pyridin-2-yl)methyl]ethane-1,2-diamine | 62402-28-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N~1~-(2-Aminoethyl)-N~2~-[(pyridin-2-yl)methyl]ethane-1,2-diamine
• 英文别名: N'-[2-(pyridin-2-ylmethylamino)ethyl]ethane-1,2-diamine
• CAS: 62402-28-2
• 化学式: C₁₀H₁₈N₄
• 分子量: 194.28
• InChiKey: ZQQBIZUQHHWSRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  63
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• 3-Imidazolyl-Indoles for the Treatment of Proliferative Diseases
  申请人：Boettcher Andreas

  公开号：US20100125064A1

  公开（公告）日：2010-05-20

  The invention relates to 3-heterocyclyl indolyl compounds capable of inhibiting the interaction between p53, or variants thereof, and MDM2 and/or MDM4, or variants thereof, respectively, said compounds having the formula I, wherein R 1 , R 2 , R 3 , R 4 , R A , Y and Y are as defined in the specification. Due to their activity, the compounds are useful in the treatment of various disorders and diseases mediated by the activity of MDM2 and/or MDM4, or variants thereof, such as inflammatory or proliferative diseases or in the protection of cells.

  本发明涉及能够抑制p53或其变体与MDM2和/或MDM4或其变体相互作用的3-杂环基吲哚化合物，其中所述化合物具有式I，其中R1、R2、R3、R4、RA、Y和Y的定义见说明书。由于其活性，这些化合物可用于治疗由MDM2和/或MDM4或其变体介导的各种疾病和疾病，例如炎症性或增殖性疾病或细胞保护。
• [EN] BLEACH ACTIVATION<br/>[FR] ACTIVATION D'UN AGENT DE BLANCHIMENT
  申请人：UNILEVER N.V.

  公开号：WO1997048787A1

  公开（公告）日：1997-12-24

  (EN) A bleach and oxidation catalyst is provided comprising a catalytically active metal complex having a poly-dentate ligand containing at least 6 hetero atoms. Such metal complexes can activate hydrogen peroxide, peroxy acids or molecular oxygen and were found to have both favourable stain removal and remarkable dye transfer inhibition properties. In addition, these complexes can be easily prepared.(FR) L'invention concerne un catalyseur de blanchiment et d'oxydation. Ce catalyseur comprend un complexe métallique présentant une activité catalytique, et possédant un ligand polydenté contenant au moins 6 hétéroatomes. Ces complexes métalliques peuvent activer le peroxyde d'hydrogène, les peroxyacides ou l'oxygène moléculaire et présentent de bonnes propriétés de détachage et d'inhibition de transfert des colorants. En outre, ces complexes sont faciles à préparer.

  一种脱色和氧化催化剂，包括包含至少6个hétéroatomes的多齿配位体的催化的活性金属复合物。这样的金属复合物能够激活氢 peroxide、 peroxy acids或分子 oxygen，并且能够表现出良好的脱色效果、显著抑制染料迁移的性质。此外，这些复合物易于制备。
• BLEACH ACTIVATION
  申请人：UNILEVER N.V.

  公开号：EP0906402A1

  公开（公告）日：1999-04-07
• 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES
  申请人：Novartis AG

  公开号：EP2142535A2

  公开（公告）日：2010-01-13
• NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR
  申请人：FUJIFILM Corporation

  公开号：US20160304730A1

  公开（公告）日：2016-10-20

  An object of the present invention is to provide a near infrared radiation-absorbing composition having favorable shielding properties in a near infrared range when used to produce cured films, a near infrared radiation cut-off filter and a production method therefor, and a camera module and a production method therefor. The near infrared radiation-absorbing composition including a copper complex formed by reacting a compound (A) having two or more coordinating atoms that form bonds using unshared electron pairs with a copper component.