| 61545-06-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• CAS: 61545-06-0
• 化学式: C16H18N2NaO7S2
• 分子量: 437.4
• InChiKey: XASVDWWWQZZSFK-ISSJOPCQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.14
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  187
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• An otorhinological drug delivery device
  申请人：Schering Oy

  公开号：EP1438942A1

  公开（公告）日：2004-07-21

  The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elastomer composition selected from the group consisting of poly(dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms of the siloxane units, a siloxane-based elastomer comprising poly(alkylene oxide) groups and mixtures thereof.

  本发明涉及一种包含至少一种药用活性剂的耳鼻喉给药装置。根据本发明，该装置包括一个包含所述至少一种药物活性剂的芯体，其中所述芯体由弹性体组合物制成，该弹性体组合物选自聚（二甲基硅氧烷）、硅氧烷基弹性体（包含连接到硅氧烷单元S原子上的3,3,3-三氟丙基）、硅氧烷基弹性体（包含聚（环氧烷）基团）及其混合物组成的组。
• Controlled release composition
  申请人：Xu Jianjian

  公开号：US10335370B2

  公开（公告）日：2019-07-02

  The present disclosure provides a controlled release composition comprising a plurality of microparticles and a matrix, wherein: the plurality of microparticles comprises a first material; the matrix comprises a second material; and the melting temperature of the first material is higher than the melting temperature of the second material. Also provided are methods of making and using the same.

  本公开提供了一种控释组合物，包括多个微颗粒和基质，其中：多个微颗粒包括第一种材料；基质包括第二种材料；第一种材料的熔化温度高于第二种材料的熔化温度。此外，还提供了制作和使用上述材料的方法。
• DIPEPTIDE-BASED PRODRUG LINKERS FOR ALIPHATIC AMINE-CONTAINING DRUGS
  申请人：Ascendis Pharma A/S

  公开号：EP2525830B1

  公开（公告）日：2016-05-11
• SILK RESERVOIRS FOR DRUG DELIVERY
  申请人：Trustees of Tufts College

  公开号：EP2827884A1

  公开（公告）日：2015-01-28
• METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION
  申请人：LeMahieu Edward

  公开号：US20080066741A1

  公开（公告）日：2008-03-20

  Systems and methods for delivery of a drug to the respiratory system of a patient are provided, where the drug is supplied in purified air at a positive pressure relative to atmospheric pressure. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the purified air stream in aerosol, nebulized, or vaporized form.