4-methyl-N,N-di(propan-2-yl)benzenecarboximidamide | 1373613-16-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-N,N-di(propan-2-yl)benzenecarboximidamide
• CAS: 1373613-16-1
• 化学式: C₁₄H₂₂N₂
• 分子量: 218.342
• InChiKey: FAFLTEGPRZYYRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  27.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二异丙基氨腈 、 potassium (4-methylphenyl)trifluoroborate 在 palladium(II) trifluoroacetate 、 三氟乙酸 、 6-甲基-2,2′-二吡啶 作用下， 以 甲醇 为溶剂， 反应 0.33h， 以24%的产率得到4-methyl-N,N-di(propan-2-yl)benzenecarboximidamide
  参考文献：
  名称：

  Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

  摘要：

  A fast and convenient synthesis of arylamidines starting from readily available potassium aryltrifluoroborates and cyanamides is reported. The coupling was achieved by Pd(II)-catalysis in a one step 20 min microwave protocol using Pd(O2CCF3), 6-methyl-2,2'-bipyridyl, TFA, and MeOH, providing the corresponding arylamidines in moderate to excellent yields.

  DOI：

  10.1021/ol300813c

文献信息

• Polymerization Catalyst Comprising Amidine Ligand
  申请人：Ijpeij Edwin

  公开号：US20090012246A1

  公开（公告）日：2009-01-08

  The invention relates to a process for the preparation of a polymer comprising at least one aliphatic or aromatic hydrocarbyl C 2-20 olefin in the presence of an ionic catalyst comprising an organometallic compound and an activator, and optionally a scavenger, characterized in that the organometallic compound is a compound according to formula (1): where: M is a metal of group 3, 4, 5, 6 or 7, or the lanthanide series, and p is the valency of the metal M, A represents a neutral or anionic spectator ligand whose valency v is 0, 1 or 2, and q is an integer denoting the number of spectator ligands A, Z is an optional bridging moiety, n is the integer number of parallel bridging moieties Z, Y is an amidine-containing spectator ligand represented by formula (2): wherein the amidine-containing ligand is covalently bonded to the metal M via the imine nitrogen atom, Sub 1 is a substituent, which comprises a group 14 atom through which Sub 1 is bonded to the imine carbon atom. Sub 2 is a substituent, which comprises a heteroatom of group 15-16, through which Sub 2 is bonded to the imine carbon atom, r is an integer >0, L is an optional neutral Lewis basic ligand, j is an integer denoting the number of neutral ligands L, and X is an anionic ligand. The invention further relates to a organometallic compound according to formula (1) and a process for the preparation of this compound as well as to a UHMWPE having a weight average molecular weight of at least 4.000 kg/mol and a molecular weight distribution M w /M n of less than 2.6.

  本发明涉及一种制备聚合物的方法，该聚合物包含至少一种脂肪族或芳香族C2-20烯烃，在离子催化剂的存在下进行。该离子催化剂包括一个有机金属化合物和一个活化剂，以及可选的清除剂。其中，所述有机金属化合物是符合以下公式（1）的化合物： 其中：M是3、4、5、6或7族金属或稀土系列金属，p是金属M的价，A代表中性或负离子观察配体，其价为0、1或2，q是表示观察配体A的数量的整数，Z是可选的桥接基团，n是平行桥接基团Z的整数，Y是含有酰胺基的观察配体，其由以下公式（2）表示： 其中，含有酰胺基的配体通过亚胺氮原子与金属M共价键合，Sub1是一个取代基，其中包括一个14族元素基团，通过Sub1与亚胺碳原子键合。Sub2是一个取代基，其中包括一个15-16族杂原子，通过Sub2与亚胺碳原子键合。r是大于0的整数，L是可选的中性路易斯碱配体，j是表示中性配体L的数量的整数，X是一个负离子配体。本发明还涉及符合公式（1）的有机金属化合物的制备方法，以及具有重量平均分子量至少为4.000 kg/mol，分子量分布Mw/Mn小于2.6的超高分子量聚乙烯的制备方法。
• POLIMERIZATION CATALYST COMPRISING AN AMIDINE LIGAND
  申请人：Lanxess Elastomers B.V.

  公开号：EP1730205B1

  公开（公告）日：2012-09-26
• US7956140B2
  申请人：——

  公开号：US7956140B2

  公开（公告）日：2011-06-07
• [EN] POLIMERIZATION CATALYST COMPRISING AN AMIDINE LIGAND<br/>[FR] CATALYSEUR DE POLYMERISATION COMPRENANT UN LIGAND AMIDINE
  申请人：DSM IP ASSETS BV

  公开号：WO2005090418A1

  公开（公告）日：2005-09-29

  The invention relates to a process for the preparation of a polymer comprising at least one aliphatic or aromatic hydrocarbyl C2-20 olefin in the presence of an ionic catalyst, comprising an organometallic compound and an activator, and optionally a scavenger, characterized in that the organometallic compound is a compound according to formula (1): where: M is a metal of group 3, 4, 5, 6 or 7, or the lanthanide series, and p is the valency of the metal M, A represents a neutral or anionic spectator ligand whose valency v is 0, 1 or 2, and q is an integer denoting the number of spectator ligands A, Z is an optional bridging moiety, n is the integer number of parallel bridging moieties Z, Y is an amidine-containing spectator ligand represented by formula (2): wherein the amidine-containing ligand is covalently bonded to the metal M via the imine nitrogen atom, Sub1 is a substituent, which comprises a group 14 atom through which Sub1 is bonded to the imine carbon atom. Sub2 is a substituent, which comprises a heteroatom of group 15-16, through which Sub2 is bonded to the imine carbon atom, r is an integer > 0, L is an optional neutral Lewis basic ligand, j is an integer denoting the number of neutral ligands L, and X is an anionic ligand. The invention further relates to a organometallic compound according to formula (1) and a process for the preparation of this compound as well as to a UHMWPE having a weight average molecular weight of at least 4.000 kg/mol and a molecular weight distribution Mw/Mn of less than 2.6.
• Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates
  作者：Jonas Sävmarker、Jonas Rydfjord、Johan Gising、Luke R. Odell、Mats Larhed

  DOI：10.1021/ol300813c

  日期：2012.5.4

  A fast and convenient synthesis of arylamidines starting from readily available potassium aryltrifluoroborates and cyanamides is reported. The coupling was achieved by Pd(II)-catalysis in a one step 20 min microwave protocol using Pd(O2CCF3), 6-methyl-2,2'-bipyridyl, TFA, and MeOH, providing the corresponding arylamidines in moderate to excellent yields.