| 1191927-96-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• CAS: 1191927-96-4
• 化学式: C₁₀H₈O₆
• 分子量: 224.17
• InChiKey: HDGRUVBMALFFSD-FLDQZLTMSA-N

反应信息

• 作为产物：
  描述：

  在 甲烷磺酸 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.0h， 以89%的产率得到
  参考文献：
  名称：

  Synthesis of 9-oxa-noradamantane derivative, an aesthetically pleasing ‘oxa-basket’

  摘要：

  A simple protocol for the synthesis of an aesthetically pleasing 'oxa-basket' (5-methoxy-2,8,13-trioxapentacyclo[7.2.1.1.(5,12)0.(4,11)0(6,10)]tridecane-3,7-dione), possessing 9-oxa-noradamantane core, is described. The readily available diquinane based dichloro bis-gamma-lactone precursor upon treatment with MeSO3H furnished dichloro 'oxa-basket' which was dechlorinated using TBTH/AIBN to obtain the title compound. The key role of the chlorines was demonstrated by replacement with hydrogen or allyl substituents which redirects the cascade to simple hydrolysis products. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.143