6-hydroxy-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-bromopyrimidine-4-carboxylic acid methyl ester | 1190410-22-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 6-hydroxy-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-bromopyrimidine-4-carboxylic acid methyl ester
• 英文别名: 6-Hydroxy-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-bromopyrimidine-4-carboxylic acid methyl ester；methyl 5-bromo-2-(4-chloro-2-fluoro-3-methoxyphenyl)-6-oxo-1H-pyrimidine-4-carboxylate
• CAS: 1190410-22-0
• 化学式: C₁₃H₉BrClFN₂O₄
• 分子量: 391.581
• InChiKey: HURLMBGYGQNMEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  77
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  6-hydroxy-2-(4-chloro-2-fluoro-3-methoxyphenyl)-pyrimidine-4-carboxylic acid methyl ester 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 2.0h， 以63%的产率得到6-hydroxy-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-bromopyrimidine-4-carboxylic acid methyl ester
  参考文献：
  名称：

  2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES

  摘要：

  2-(取代苯基)-6-羟基或烷氧基-5-取代-4-嘧啶羧酸及其衍生物是除草剂，具有广谱杂草控制作用。

  公开号：

  US20090264293A1

文献信息

• 2-(substituted phenyl)-6-hydroxy or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides
  申请人：Dow AgroSciences LLC

  公开号：US07833940B2

  公开（公告）日：2010-11-16

  2-(Substituted phenyl)-6-hydroxy or alkoxy-5-substituted-4-pyrimidinecarboxylic acids and their derivatives are herbicides demonstrating a broad spectrum of weed control.

  2-(取代苯基)-6-羟基或烷氧基-5-取代-4-嘧啶羧酸及其衍生物是除草剂，具有广谱的杂草控制作用。
• 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides
  申请人：Dow AgroSciences LLC

  公开号：EP2279178B1

  公开（公告）日：2015-05-20
• US7833940B2
  申请人：——

  公开号：US7833940B2

  公开（公告）日：2010-11-16
• [EN] 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES<br/>[FR] 2-(PHÉNYL SUBSTITUÉ)-6-HYDROXY OU ALCOXY-5-SUBSTITUÉ-4-PYRIMIDINE CARBOXYLATES ET LEUR UTILISATION COMME HERBICIDES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2009129291A1

  公开（公告）日：2009-10-22

  2-(Substituted phenyl)-6- hydroxy or alkoxy-5-substituted-4-pyrimidinecarboxylic acids and their derivatives are herbicides demonstrating a broad spectrum of weed control.
• 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES
  申请人：Siddall Thomas L.

  公开号：US20090264293A1

  公开（公告）日：2009-10-22

  2-(Substituted phenyl)-6-hydroxy or alkoxy-5-substituted-4-pyrimidinecarboxylic acids and their derivatives are herbicides demonstrating a broad spectrum of weed control.

  2-(取代苯基)-6-羟基或烷氧基-5-取代-4-嘧啶羧酸及其衍生物是除草剂，具有广谱杂草控制作用。