1-(tert-butoxycarbonyloxy)-2,4,6-trimethylbenzene | 160236-32-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(tert-butoxycarbonyloxy)-2,4,6-trimethylbenzene
• 英文别名: 2-(tert-butoxycarbonyloxy)-1,3,5-trimethylbenzene；Tert-butyl (2,4,6-trimethylphenyl) carbonate
• CAS: 160236-32-8
• 化学式: C₁₄H₂₀O₃
• 分子量: 236.311
• InChiKey: KEXASNLXQQXZHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,4,6-三甲酚 、 二碳酸二叔丁酯 在 三苯基膦 作用下， 反应 17.0h， 以81%的产率得到1-(tert-butoxycarbonyloxy)-2,4,6-trimethylbenzene
  参考文献：
  名称：

  Triphenylphosphine as a Novel Organocatalyst for Chemoselective O-tert-Butoxycarbonylation of Phenols

  摘要：

  描述了一种新颖的有机催化过程，用于在中性及无溶剂条件下对酚类化合物进行化学选择性的O-叔丁氧羰基化反应。

  DOI：

  10.1055/s-2008-1072565

文献信息

• Organocatalytic Methods for Chemoselective <i>O</i>-<i>tert</i>-Butoxycarbonylation of Phenols and Their Regeneration from the <i>O</i>-<i>t</i>-Boc Derivatives
  作者：Sunay V. Chankeshwara、Rajesh Chebolu、Asit K. Chakraborti

  DOI：10.1021/jo8013325

  日期：2008.11.7

  without any side reactions (bromination, addition of CBr3 to a double bond, and formation of symmetrical diaryl carbonates, cyclic carbonates, or carbonic-carbonic anhydrides). The parent phenols are regenerated from the O-t-Boc derivatives by the catalyst system CBr4-PPh3 without affecting other protecting groups (aryl alkyl ether, alkyl ester, and thioacetal) or competitive side reaction such as bromination

  四溴化碳（CBr4）催化官能化酚的O-叔丁氧羰基化反应，而没有任何副反应（溴化，将CBr3加成双键，并形成对称的碳酸二芳基酯，环状碳酸酯或碳酸碳酐）。母体酚是通过催化剂体系 -PPh3从Ot-Boc衍生物再生而不会影响其他保护基团（芳基烷基醚，烷基酯和硫代缩醛）或竞争性副反应，例如溴化，腈（来自NO2）和α，发生α-二溴代烯烃（带有CHO / COMe）和酯交换反应（带有CO2Me / Et）。
• LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE
  申请人：ADEKA CORPORATION

  公开号：US20150291772A1

  公开（公告）日：2015-10-15

  A latent additive represented by general formula (1): wherein A is a 5- or 6-membered aromatic or heterocyclic ring; R 1 and R 2 are each hydrogen, halogen, cyano, hydroxyl, nitro, carboxyl, optionally substituted C1-C40 alkyl, C6-C20 aryl, C7-C20 arylalkyl, or C2-C20 heterocyclic ring-containing group; and R 4 is C1-C20 alkyl, C2-C20 alkenyl, C6-C20 aryl, C7-C20 arylalkyl, C2-C20 heterocyclic ring-containing group, or trialkylsilyl.
• ANTIOXIDANT FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME
  申请人：ADEKA CORPORATION

  公开号：US20170198117A1

  公开（公告）日：2017-07-13

  Disclosed is an antioxidant for a thermoplastic resin that provides an excellent oxidation-preventing effect to a thermoplastic resin and that has an excellent effect of preventing a change in color caused by nitrogen oxides. Specifically, a compound represented by any of General Formulae (2) to (4), particularly a compound in which R 2 in the formulae is an alkyl group having 1 to 8 carbon atoms whose terminal on an oxygen atom side is linked with —CO—O—, is used as the antioxidant for a thermoplastic resin. Details of General Formulae (2) to (4) are as described in the description.
• US9777138B2
  申请人：——

  公开号：US9777138B2

  公开（公告）日：2017-10-03