| 214355-13-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 金属杂环化合物
• CAS: 214355-13-2
• 化学式: C₁₉H₄₂O₄P₂Pt
• 分子量: 591.568
• InChiKey: LXKXASXITUFGEO-FKWOBBRMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  盐酸 、 以 甲醇 、 二氯甲烷 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  Chirale Bisphosphane VI. Chelatkomplexe von Platin(II) mit racemischen und optisch reinen trans-Cyclopentan-1,2-diyl-bis(phosphonigsäurediester)- und trans-Cyclopentan-1,2-diyl-bis(phosphonigsäurediamid)-Liganden: Synthesen, Strukturen und C–H-Aktivierungsreaktionen

  摘要：

  New bidentate ligands of the type C5H8(PX2)(2) [PX2 = P(OMe)(2) (2), P(OPh)(2) (3), P[OCH(Me)Et-(S)](2) (4), P[OC6H9(Me)Pr-i-(1R)](2) (5), P[OCH(CO2Pri)-(R)-](2) (6), P[N(CH2)(5)-cyclo](2) (7), P[N(CH2)(4)O-cyclo](2) (8)] were prepared from rac-C5H8(PCl2)(2) (1) and the corresponding alcohols, diols, and secondary amines. These reacted with [(1,5-C8H12)Pt(CH2CMe3)(2)] to give Pt(II) derivatives, [C5H8{P(OR)(2)}(2)Pt(CH2CMe3)(2)] [P(OR)(2) = P(OMe)(2) (9), P(OPh)(2) (10), P[OCH(Me)Et-(S)](2) (11), P[OC6H9(Me)Pr-i-(1R)](2) (12), P[OCH(CO2Pri-(R)-](2) (13)] and [C5H8{P(NR2)(2)}(2)Pt(CH2CMe3)(2) [P(NR2)(2) = P[N(CH2)(5)-cyclo](2) (14), P[N(CH2)(4)O-cyclo](2) (15)], respectively. Controlled acidolysis of 9, 10, 12, and 13 yielded the chloro neopentyls [C5H8{P(OR)(2)}(2)Pt(Cl)CH2CMe3] [(P(OR)(2) = P(OMe)(2) (16), P(OPh)(2) (17), P[OC6H9(Me)Pr-i-(1R)](2) (18), P[OCH(CO2Pri)-(R)-](2) (19)]. Their P-N-bonded analogues [C5H8{P(NR2)(2)}(2)Pt(Cl)CH2CMe3] [P(NR2)(2) = P[N(CH2)(5)-cyclo](2) (20), P[N(CH2)(4)O-cyclo], (21)] were obtained by substituting the diene ligand of [(1,5-C8H12)Pt(Cl)CH2CMe3] for bidentates 7 and 8. Treatment of 20 and 21 with Na[BH(OMe)(3)] in THF provided neopentyl hydrides, [C5H8{P(NR2)(2)}(2)Pt(H)CH2CMe3] [P(NR2)(2) = P[N(CH2)(4)-cyclo](2) (23), P[N(CH2)(4)O-cyclo](2) (24)], which exhibited similar inertness toward reductive elimination at temperatures below 60 degrees C as did the previously investigated P-C-substituted derivative [C5H8{P(C6H11-cyclo)(2)}(2)Pt(H)CH2CMe3]. The crystal structures of [(1S, 2S)-C5H8 {P[OC6H9(Me)Pri-(1R)](2)}(2)Pt(CH2CMe3)(2)], (1S,2S)-12, [C5H8{P[N(CH2)(4)O-cyclo](2)}(2)Pt(CH2CMe3)(2)], 15, [(1S,2S)-C5H8{P[OC6H9(Me)Pr-i- (1R)](2)}(2)Pt(Cl)CH2CMe3], (1S,2S)-18, and also of [C5H8{P(OPh)(2)}PtCl2], 22, were determined by X-ray diffraction.

  DOI：

  10.1016/s0022-328x(98)00617-2
• 作为产物：
  描述：

  (1,5-cyclooctadiene)dineopentylplatinum(II) 、 以 四氢呋喃 为溶剂， 以85%的产率得到
  参考文献：
  名称：

  Chirale Bisphosphane VI. Chelatkomplexe von Platin(II) mit racemischen und optisch reinen trans-Cyclopentan-1,2-diyl-bis(phosphonigsäurediester)- und trans-Cyclopentan-1,2-diyl-bis(phosphonigsäurediamid)-Liganden: Synthesen, Strukturen und C–H-Aktivierungsreaktionen

  摘要：

  New bidentate ligands of the type C5H8(PX2)(2) [PX2 = P(OMe)(2) (2), P(OPh)(2) (3), P[OCH(Me)Et-(S)](2) (4), P[OC6H9(Me)Pr-i-(1R)](2) (5), P[OCH(CO2Pri)-(R)-](2) (6), P[N(CH2)(5)-cyclo](2) (7), P[N(CH2)(4)O-cyclo](2) (8)] were prepared from rac-C5H8(PCl2)(2) (1) and the corresponding alcohols, diols, and secondary amines. These reacted with [(1,5-C8H12)Pt(CH2CMe3)(2)] to give Pt(II) derivatives, [C5H8{P(OR)(2)}(2)Pt(CH2CMe3)(2)] [P(OR)(2) = P(OMe)(2) (9), P(OPh)(2) (10), P[OCH(Me)Et-(S)](2) (11), P[OC6H9(Me)Pr-i-(1R)](2) (12), P[OCH(CO2Pri-(R)-](2) (13)] and [C5H8{P(NR2)(2)}(2)Pt(CH2CMe3)(2) [P(NR2)(2) = P[N(CH2)(5)-cyclo](2) (14), P[N(CH2)(4)O-cyclo](2) (15)], respectively. Controlled acidolysis of 9, 10, 12, and 13 yielded the chloro neopentyls [C5H8{P(OR)(2)}(2)Pt(Cl)CH2CMe3] [(P(OR)(2) = P(OMe)(2) (16), P(OPh)(2) (17), P[OC6H9(Me)Pr-i-(1R)](2) (18), P[OCH(CO2Pri)-(R)-](2) (19)]. Their P-N-bonded analogues [C5H8{P(NR2)(2)}(2)Pt(Cl)CH2CMe3] [P(NR2)(2) = P[N(CH2)(5)-cyclo](2) (20), P[N(CH2)(4)O-cyclo], (21)] were obtained by substituting the diene ligand of [(1,5-C8H12)Pt(Cl)CH2CMe3] for bidentates 7 and 8. Treatment of 20 and 21 with Na[BH(OMe)(3)] in THF provided neopentyl hydrides, [C5H8{P(NR2)(2)}(2)Pt(H)CH2CMe3] [P(NR2)(2) = P[N(CH2)(4)-cyclo](2) (23), P[N(CH2)(4)O-cyclo](2) (24)], which exhibited similar inertness toward reductive elimination at temperatures below 60 degrees C as did the previously investigated P-C-substituted derivative [C5H8{P(C6H11-cyclo)(2)}(2)Pt(H)CH2CMe3]. The crystal structures of [(1S, 2S)-C5H8 {P[OC6H9(Me)Pri-(1R)](2)}(2)Pt(CH2CMe3)(2)], (1S,2S)-12, [C5H8{P[N(CH2)(4)O-cyclo](2)}(2)Pt(CH2CMe3)(2)], 15, [(1S,2S)-C5H8{P[OC6H9(Me)Pr-i- (1R)](2)}(2)Pt(Cl)CH2CMe3], (1S,2S)-18, and also of [C5H8{P(OPh)(2)}PtCl2], 22, were determined by X-ray diffraction.

  DOI：

  10.1016/s0022-328x(98)00617-2