2-(2-(benzo[c][1,2,5]selenadiazol-5-yl)vinyl)-1-methylpyridin-1-ium iodide | 1242027-77-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-(benzo[c][1,2,5]selenadiazol-5-yl)vinyl)-1-methylpyridin-1-ium iodide
• CAS: 1242027-77-5
• 化学式: C₁₄H₁₂N₃Se*I
• 分子量: 428.134
• InChiKey: LEQXRURYDKUJBW-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.31
• 重原子数：
  19.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  29.66
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  碘化1,2-二甲基吡啶鎓 、 2,1,3-Benzoselenadiazol-5-carbaldehyd 以 乙醇 为溶剂， 反应 0.75h， 生成 2-(2-(benzo[c][1,2,5]selenadiazol-5-yl)vinyl)-1-methylpyridin-1-ium iodide
  参考文献：
  名称：

  The determination of thiols based using a probe that utilizes both an absorption red-shift and fluorescence enhancement

  摘要：

  A pyridylvinylene derivative containing piazselenole displayed high selectivity toward glutathione in the presence of other biorelevant analytes. The compound exhibited a 19 run red-shift in absorption spectra and similar to 3-fold fluorescence intensity enhancement: in addition, it was possible to detect micromolar amounts of glutathione quantitatively using both red-shift absorbance and enhanced fluorescence. The mechanism of the reaction between the modified pyridylvinylene derivative and glutathione was confirmed using ESI-MS and absorption/fluorescence spectra. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2009.11.011