3,4,5-tris(tetraethyleneoxy)benzoyl chloride | 887501-25-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,4,5-tris(tetraethyleneoxy)benzoyl chloride
• 英文别名: Cl(O)C-Ph((EO)4OMe)3；3,4,5-Tris[(2,5,8,11-tetraoxatridecan-13-yl)oxy]benzoyl chloride；3,4,5-tris[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]benzoyl chloride
• CAS: 887501-25-9
• 化学式: C₃₄H₅₉ClO₁₆
• 分子量: 759.286
• InChiKey: JGNVRJQGMZCGQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  51
• 可旋转键数：
  40
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  156
• 氢给体数：
  0
• 氢受体数：
  16

反应信息

• 作为反应物：
  描述：

  3,4,5-tris(tetraethyleneoxy)benzoyl chloride 、 7,7'-(quinoxaline-5,8-diyl)bis(9,9-bis((S)-3,7-dimethyloctyl)-9H-fluoren-2-amine) 在 三乙胺 作用下， 以 氯仿 为溶剂， 以76%的产率得到
  参考文献：
  名称：

  Multicolour self-assembled particles of fluorene-based bolaamphiphiles

  摘要：

  基于芴的亲水型球状聚集体在水中的自组装形成荧光纳米颗粒，其发射颜色可调，覆盖整个可见光范围，甚至包括白色。

  DOI：

  10.1039/b822943k
• 作为产物：
  描述：

  HOOC-Ph((EO)4OMe)3 在 N,N-二甲基甲酰胺 草酰氯 作用下， 以 二氯甲烷 为溶剂， 反应 1.17h， 生成 3,4,5-tris(tetraethyleneoxy)benzoyl chloride
  参考文献：
  名称：

  WO2007/6700

  摘要：

  公开号：

文献信息

• Non-coordinating anions assemble cyanine amphiphiles into ultra-small fluorescent nanoparticles
  作者：Ievgen Shulov、Youri Arntz、Yves Mély、Vasyl G. Pivovarenko、Andrey S. Klymchenko

  DOI：10.1039/c6cc03716j

  日期：——

  A non-coordinating anion, fluorinated tetraphenylborate, assembles specially designed cationic cyanine amphiphiles into 7–8 nm fluorescent nanoparticles that are >40-fold brighter than a single cyanine dye.

  一种不协同的阴离子，氟化四苯基硼酸盐，将特别设计的阳离子青霉烷两亲分子组装成直径为7-8纳米的荧光纳米颗粒，其亮度比单个青霉烷染料高出40倍以上。
• MODIFIED POLY(PROPYLENE-IMINE) DENDRIMERS AND THEIR USE AS TRANSFECTION AGENTS FOR AMIONIC BIOACTIVE FACTORS ( as amended
  申请人：Tack Frederik

  公开号：US20100298403A1

  公开（公告）日：2010-11-25

  The present invention is concerned with modified poly-(propylene imine) dendrimers, comprising cationic internal ammonium groups and external non-toxic endgroups, pharmaceutical compositions comprising said dendrimers, methods for the production of said dendrimers and their use as transfections agents for anionic bioactive therapeutic factors, for use in gene therapy, in particular for the treatment of cancer. The modified poly-(propylene imine) dendrimer of generation 1, 2, 3, 4 or 5, also comprising incomplete dendrimers and mixtures thereof, comprising external end groups and internal amine functions are characterized in that: (a) substantially all external endgroups are groups of formula (I) wherein R is a radical selected from the group of C 1-10 alkyl, polyethylene glycol radical and polyethylene glycol gallyl radical; and (b) substantially all internal amine functions are quaternary cationic ammonium functions. Most preferred are the quaternized compounds DAB-dendr-(NHCOCH 3 ) 4 , DAB-dendr-(NHCOCH 3 ) 8 , DAB-dendr-(NHCOCH 3 ) 16 , DAB-dendr-(NHCOCH 3 ) 32 , DAB-dendr-(NHCOCH 3 ) 64 , DAB-dendr-(NHCOPh((EO) 4 OMe) 3 ) 4 , DAB-dendr-(NHCOPh((EO) 4 OMe) 3 ) 8 , DAB-dendr-(NHCOPh((EO) 4 OMe) 3 ) 16 , DAB-dendr-(NHCOPh((EO) 4 OMe) 3 ) 32 and DAB-dendr-(NHCOPh((EO) 4 OMe) 3 ) 64 .
• [EN] DENDRITIC MOLECULES, PROCESS FOR THEIR PREPARATION AND USES THEREOF<br/>[FR] MOLÉCULES DENDRITIQUES, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS UTILISATIONS
  申请人：[en]SUPERBRANCHE

  公开号：WO2023198813A1

  公开（公告）日：2023-10-19

  The present invention relates to polyfunctional organic dendritic molecules derived from alkyl phosphonates or esters, to a process for preparing the same and to the use thereof, in particular as drug carriers or contrast agents.