2-amino-N-(ethylideneamino)benzamide | 860588-22-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-amino-N-(ethylideneamino)benzamide
• CAS: 860588-22-3
• 化学式: C₉H₁₁N₃O
• 分子量: 177.206
• InChiKey: HKBDDJJCOJAVHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.0
• 重原子数：
  13.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  67.48
• 氢给体数：
  2.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  2-amino-N-(ethylideneamino)benzamide 以 氘代氯仿 为溶剂， 反应 336.0h， 以98%的产率得到2-methyl-1,2-dihydroquinazolin-4(3)-one
  参考文献：
  名称：

  Anthranoylhydrazones of aliphatic aldehydes and their cyclization to quinazolin-4-one derivatives

  摘要：

  The isomeric transition of 2-aminobenzoylhydrazones of aliphatic aldehydes 2-H2NC6H4CONHN=CHAlk (Alk = Me, Et, Pr, Bu) in chloroform-d(1) solution into the cyclic 1,2-dihydroquinazolin-4-one form has been studied. The structure of the obtained compounds was demonstrated by methods of H-1 and C-13 NMR spectroscopy.

  DOI：

  10.1007/s10593-009-0364-x
• 作为产物：
  描述：

  乙醛 、 2-氨基亚苯基肼 以 苯 为溶剂， 反应 2.0h， 以55%的产率得到2-amino-N-(ethylideneamino)benzamide
  参考文献：
  名称：

  Anthranoylhydrazones of aliphatic aldehydes and their cyclization to quinazolin-4-one derivatives

  摘要：

  The isomeric transition of 2-aminobenzoylhydrazones of aliphatic aldehydes 2-H2NC6H4CONHN=CHAlk (Alk = Me, Et, Pr, Bu) in chloroform-d(1) solution into the cyclic 1,2-dihydroquinazolin-4-one form has been studied. The structure of the obtained compounds was demonstrated by methods of H-1 and C-13 NMR spectroscopy.

  DOI：

  10.1007/s10593-009-0364-x