| 1186530-64-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1186530-64-2
• 化学式: C₄₉H₇₇NO₁₀SSi₃
• 分子量: 956.474
• InChiKey: LNMDGMVGKWBENS-MRPWXNQFSA-N

反应信息

• 作为反应物：
  描述：

  在 5%-palladium/activated carbon 、 氢气 作用下， 以 乙醇 为溶剂， 以89%的产率得到[(3aR,4R,6S,8S,8aS,8bS)-8-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dimethyl-4,6,7,8,8a,8b-hexahydro-3aH-[1,3]dioxolo[4,5-a]pyrrolizin-4-yl]methoxy-tert-butyl-diphenylsilane
  参考文献：
  名称：

  Total synthesis of the proposed structures of hyacinthacines C2, C3, and their C5-epimers

  摘要：

  Synthesis and structural confirmation of highly oxygenated pyrrolizicline alkaloids, hyacinthacines C-2 [(1S,2R,3R,5R,7S,7aR)-3,5-hydroxymethyl-1,2,7-trihydroxypyrrolizidine], C-3[1S,2R,3R,5S,7R,7aR)-3,5-hydroxymethyl-1,2,7-trihydroxypyrrolizidine], and their C5-epimers were achieved on the basis of the highly divergent method employing (S)-(-)-2-pyrrolidone-5-carboxylic acid as the starting material. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.072
• 作为产物：
  描述：

  benzyl (3aS,4S,6R,6aR)-4-[(1S,3R)-1,4-bis[[tert-butyl(dimethyl)silyl]oxy]-3-hydroxybutyl]-6-[[tert-butyl(diphenyl)silyl]oxymethyl]-2,2-dimethyl-3a,4,6,6a-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate 、 甲基磺酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以74%的产率得到
  参考文献：
  名称：

  Total synthesis of the proposed structures of hyacinthacines C2, C3, and their C5-epimers

  摘要：

  Synthesis and structural confirmation of highly oxygenated pyrrolizicline alkaloids, hyacinthacines C-2 [(1S,2R,3R,5R,7S,7aR)-3,5-hydroxymethyl-1,2,7-trihydroxypyrrolizidine], C-3[1S,2R,3R,5S,7R,7aR)-3,5-hydroxymethyl-1,2,7-trihydroxypyrrolizidine], and their C5-epimers were achieved on the basis of the highly divergent method employing (S)-(-)-2-pyrrolidone-5-carboxylic acid as the starting material. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.072