1-(4-{2-[5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazole-4-carbonyl]-1H-indol-6-ylmethyl}-piperazin-1-yl)-ethanone | 1265230-79-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1-(4-{2-[5-amino-1-(2-methyl-1H-benzimidazol-5-yl)-1H-pyrazole-4-carbonyl]-1H-indol-6-ylmethyl}-piperazin-1-yl)-ethanone
• 英文别名: 1-[4-[[2-[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazole-4-carbonyl]-1H-indol-6-yl]methyl]piperazin-1-yl]ethanone
• CAS: 1265230-79-2
• 化学式: C₂₇H₂₈N₈O₂
• 分子量: 496.572
• InChiKey: GZRXWBJYUJUZNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  37
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  129
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• RADIATION-SENSITIVE COLORED COMPOSITION, COLORED CURED FILM, COLOR FILTER AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, LIQUID CRYSTAL DISPLAY APPARATUS, AND METHOD OF PRODUCING DYE
  申请人：USHIJIMA Kenta

  公开号：US20120235099A1

  公开（公告）日：2012-09-20

  The object of the present invention is to provide a radiation-sensitive colored composition which can supress the generation of the contamination of the device. A radiation-sensitive colored composition including: (A) a dye containing of from 10 ppm to 1000 ppm of a halogen ion; (B) a polymerizable compound; and (C) a solvent.

  本发明的目的是提供一种辐射敏感的着色组合物，可以抑制器件的污染产生。一种辐射敏感的着色组合物，包括：（A）一种含有10 ppm至1000 ppm卤离子的染料；（B）一种可聚合化合物；和（C）一种溶剂。
• Aminopyrazole Derivative
  申请人：Taka Naoki

  公开号：US20120208811A1

  公开（公告）日：2012-08-16

  A compound represented by formula (I) or a pharmacologically acceptable salt thereof, which can inhibit a fibroblast growth factor receptor (FGFR) family kinase in cancer tissues. (In the formula, A represents a 5- to 10-membered heteroaryl group, or a C 6-10 aryl group; R 1 and R 2 independently represent H, OH, X, CN, NO 2 , a C 1-4 haloalkyl group, a C 1-6 alkyl group, or the like ; R 3 represents H, a C 1-5 alkyl group, a C 6-10 aryl group, a C 1-5 alkyl group, or a C 1-4 haloalkyl group; and R 4 represents H, X, a C 1-3 alkyl group, a C 1-4 haloalkyl group, OH, CN, NO 2 , or the like.)

  化合物(I)或其药学上可接受的盐，可以抑制癌组织中的成纤维细胞生长因子受体（FGFR）家族激酶。在公式中，A代表5-至10-成员的杂环芳基基团或C6-10芳基基团；R1和R2独立地表示H、OH、X、CN、NO2、C1-4卤代烷基、C1-6烷基或类似物；R3表示H、C1-5烷基、C6-10芳基基团、C1-5烷基或C1-4卤代烷基；R4表示H、X、C1-3烷基、C1-4卤代烷基、OH、CN、 或类似物。
• Titanium black dispersion composition for forming light blocking film and method of producing the same, black radiation-sensitive composition, black cured film, solid-state imaging element, and method of producing black cured film
  申请人：Fujifilm Corporation

  公开号：EP2472330A1

  公开（公告）日：2012-07-04

  The invention provides a titanium black dispersion composition comprising: (A) a dispersed material comprising titanium black and Si atoms; (B) a dispersant; and (C) an organic solvent, wherein 90% or more of the dispersed material has a particle diameter in a range of from 16 nm to 30 nm, and a content ratio of Si atoms to Ti atoms in the dispersed material, represented by Si/Ti, is from 0.20 to 0.50 by mass.

  本发明提供了一种钛黑分散组合物，包括 (A) 由钛黑和硅原子组成的分散材料； (B) 一种分散剂；以及 (C) 有机溶剂，其中 90% 或更多的分散材料的颗粒直径范围为 16 nm 至 30 nm，分散材料中 Si 原子与 Ti 原子的含量比（以质量表示）为 0.20 至 0.50（Si/Ti）。
• DISPERSION COMPOSITION, AND CURABLE COMPOSITION, TRANSPARENT FILM, MICROLENS AND SOLID-STATE IMAGING ELEMENT USING SAME
  申请人：FUJIFILM Corporation

  公开号：EP2891685A1

  公开（公告）日：2015-07-08

  Provided are a dispersion composition which has a high refractive index and has a high dispersion stability, a curable composition using the same, a transparent film, a microlens, and a solid-state imaging device. A dispersion composition containing metal oxide particles having a primary particle diameter of 1 nm to 100 nm (A), a polymer compound having an acid value of 120 mgKOH/g or more, which is represented by the following Formula (1) (B), and a solvent (C). In Formula (1), R1 represents a (m+n)-valent linking group, and R2 represents a single bond or a divalent linking group. A1 represents a monovalent substituent having at least one group selected from the group consisting of an acid group, a urea group, a urethane group, a group having a coordinating oxygen atom, a group having a basic nitrogen atom, a phenol group, an alkyl group, an aryl group, a group having an alkyleneoxy chain, an imide group, an alkyloxycarbonyl group, an alkyl amino carbonyl group, a carboxylate group, a sulfonamide group, a heterocyclic group, an alkoxysilyl group, an epoxy group, an isocyanate group, and a hydroxyl group. n A1's and n R2's may be same or different. m represents a positive number of 8 or less, n represents 1 to 9, and m+n satisfies 3 to 10. P1 represents a polymer chain. m P1's may be same or different.

  本发明提供了一种具有高折射率和高分散稳定性的分散组合物、一种使用该分散组合物的固化组合物、一种透明薄膜、一种微型透镜和一种固态成像装置。 一种分散液组合物，含有主颗粒直径为 1 纳米至 100 纳米的金属氧化物颗粒（A）、酸值为 120 mgKOH/g 或更高的聚合物化合物（由下式（1）表示）（B）和溶剂（C）。 在式 (1) 中 R1 代表(m+n)价连接基团，R2 代表单键或二价连接基团。A1 代表具有至少一个基团的单价取代基，该基团选自以下组别：酸基、脲基、氨基甲酸乙酯基、具有配位氧原子的基团、具有碱性氮原子的基团、酚基、烷基、芳基、烷基、烷基醚、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、酰亚胺基、烷氧基羰基、烷基氨基羰基、羧酸基、磺酰胺基、杂环基、烷氧基硅基、环氧基、异氰酸酯基和羟基。n 个 A1 和 n 个 R2 可以相同或不同。 m 代表 8 或以下的正数，n 代表 1 至 9，m+n 满足 3 至 10。 P1 代表聚合物链。
• DISPERSION COMPOSITION, CURABLE COMPOSITION USING THE SAME, TRANSPARENT FILM, MICROLENS, AND SOLID-STATE IMAGING DEVICE
  申请人：FUJIFILM Corporation

  公开号：EP3124548A1

  公开（公告）日：2017-02-01

  Provided is a dispersion composition which has a high refractive index. The surface of a film coated from the dispersion has an excellent surface condition. Also provided is a curable composition comprising the dispersion, a transparent film, a microlens and a solid-state imaging device. The dispersion composition comprises: colourless, white or transparent metal oxide particles (A) having a primary particle diameter of 1 nm to 100 nm and a refractive index of from 1.75 to 2.70; a polymer compound (B) having an acid value of less than 120 mgKOH/g and being represented by Formula (1); and a solvent (C):         (A1-R2)̵n-R1(̵P1)m     Formula (1) wherein: R1 represents a (m+n)-valent linking group represented by any one of the following Formulae: wherein: L3 represents a trivalent group; T3 represents a single bond or a divalent linking group; and the three T3's may be the same or different; L4 represents a tetravalent group; T4 represents a single bond or a divalent linking group, and the four T4's may be the same or different; L5 represents a pentavalent group; T5 represents a single bond or a divalent linking group, and the five T5's may be the same or different; L6 represents a hexavalent group; T6 represents a single bond or a divalent linking group, and the six T6's may be the same or different; R2 represents a single bond or a divalent linking group, A1 represents a monovalent substituent having at least one group selected from the group consisting of an acid group, a urea group, a urethane group, a group having a coordinating oxygen atom, a group having a basic nitrogen atom, a phenol group, an alkyl group, an aryl group, a group having an alkyleneoxy chain, an imide group, an alkyloxycarbonyl group, an alkyl amino carbonyl group, a carboxylate group, a sulfonamide group, a heterocyclic group, an alkoxysilyl group, an epoxy group, an isocyanate group, and a hydroxyl group, n A1's and n R2's may be the same or different, m represents a positive number of 8 or less, n represents 1 to 9, and m+n satisfies 3 to 10, and P1 represents a polymer chain, and m P1's may be the same or different.

  本文提供了一种具有高折射率的分散组合物。用该分散体涂覆的薄膜表面具有极佳的表面状态。此外，还提供了一种可固化组合物，其中包括该分散液、透明薄膜、微透镜和固态成像装置。 分散体组合物包括 无色、白色或透明的金属氧化物颗粒（A），其主颗粒直径为 1 纳米至 100 纳米，折射率为 1.75 至 2.70； 聚合物化合物（B），其酸值小于 120 mgKOH/g，由式（1）表示；以及 溶剂 (C)： (A1-R2)̵n-R1(̵P1)m 式 (1) 其中 R1 代表由下式中任一个式子表示的 (m+n) 价连接基团： 其中 L3 代表三价基团；T3 代表单键或二价连接基团，三个 T3 可以相同或不同； L4 代表四价基团；T4 代表单键或二价连接基团，四个 T4 可以相同或不同；L5 代表五价基团；T5 代表单键或二价连接基团，五个 T5 可以相同或不同； L6 代表六价基团；T6 代表单键或二价连接基团，六个 T6 可以相同或不同； R2 代表单键或二价连接基团、 A1 代表一个单价取代基，该取代基至少有一个基团选自以下组别：酸基、脲基、氨基甲酸乙酯基、具有配位氧原子的基团、具有碱性氮原子的基团、酚基、烷基、芳基、烷基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、醚基、酰亚胺基、烷氧基羰基、烷基氨基羰基、羧酸基、磺酰胺基、杂环基、烷氧基硅基、环氧基、异氰酸酯基和羟基、 n 个 A1 和 n 个 R2 可以相同或不同、 m 代表 8 或以下的正数，n 代表 1 至 9，m+n 满足 3 至 10，以及 P1 代表聚合物链，m 个 P1 可以相同或不同。