p-Tolyl-phosphinsaeure | 20676-63-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-Tolyl-phosphinsaeure
• 英文别名: p-Tolylphosphonous acid；(4-methylphenyl)phosphonous acid
• CAS: 20676-63-5
• 化学式: C₇H₉O₂P
• 分子量: 156.121
• InChiKey: LBDZCXKTYIWLNB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  p-Tolyl-phosphinsaeure 、 p-Tolyl-phosphinsaeure 、 4-甲氧基苯甲醛 生成 [Chloro-(4-methoxy-phenyl)-methyl]-p-tolyl-phosphinic acid
  参考文献：
  名称：

  KARDANOV, N. A.;TIMOFEEV, A. M.;GODOVIKOV, N. N.;PETROVSKIJ, P. V.;KABACH+, DOKL. AN CCCP, 1986, 286, N 6, 1403-1407

  摘要：

  DOI：

文献信息

• NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS
  申请人：ATOBE Masakazu

  公开号：US20100029690A1

  公开（公告）日：2010-02-04

  Nitrogen-containing heterocyclic compounds represented by the following Formula (1) are provided. The compounds or salts thereof have a strong EP1 antagonistic activity when they are administered to a human or an animal, and they are useful as an effective component of a pharmaceutical agent for prophylaxis and/or treatment of an overactive bladder, for example. Furthermore, they are useful as an effective component of a pharmaceutical agent for the prophylaxis and/or treatment of symptoms including frequent urination, urinary urgency and urinary incontinence.

  提供以下式（1）所代表的含氮杂环化合物。当这些化合物或其盐被给予人类或动物时，它们具有强烈的EP1拮抗活性，并且它们作为预防或治疗过度活动膀胱的药物的有效成分是有用的，例如。此外，它们作为预防或治疗包括频繁排尿、尿急和尿失禁等症状的药物的有效成分是有用的。
• Method of producing dinitrile compounds
  申请人：Rosier Cecile

  公开号：US20060258873A1

  公开（公告）日：2006-11-16

  The present invention relates to a process for the manufacture of compounds comprising two nitrile functional groups. It relates more particularly to a process for the manufacture of dinitrile compounds from compounds comprising a nitrile functional group and an ethylenic unsaturation in the presence of a catalytic system comprising an organometallic complex and a cocatalyst of the Lewis acid type. The process of the invention comprises a stage of treatment of the reaction medium resulting from the hydrocyanation which makes it possible to extract and recover the metal element of the Lewis acid.

  本发明涉及一种制备含有两个腈官能团的化合物的方法。更具体地，涉及一种在存在包括一个有机金属配合物和一种Lewis酸类辅助催化剂的催化系统的情况下，从含有腈官能团和乙烯不饱和度的化合物制备二腈化合物的方法。本发明的方法包括处理由氢氰化反应产生的反应介质的阶段，该阶段使得能够提取和回收Lewis酸的金属元素。
• Miscible high Tg polyester/polymer blend compositions and films formed therefrom
  申请人：Hale Raymond Wesley

  公开号：US20060270806A1

  公开（公告）日：2006-11-30

  Disclosed is a high Tg polyester/polymer blend composition for a sheet or film. The composition comprises about 80 to about 99.8 percent by weight of a miscible blend of a polyester with a polymer. Also disclosed is a process for the preparation of a film or sheet from this composition. Compensationa and protective films and sheets prepared from this composition are useful for backlight displays.

  本发明公开了一种用于制作薄膜或薄片的高Tg聚酯/聚合物混合物组合物。该组合物由聚酯和聚合物的可混合混合物约占重量的80％至约99.8％组成。本发明还公开了从该组合物制备薄膜或薄片的过程。使用该组合物制备的补偿和保护膜和薄片适用于背光显示。
• Polyphenylene ether resin composition of improved heat stability and shaped articles thereof
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0036278A1

  公开（公告）日：1981-09-23

  A polyphenylene ether resin composition having improved heat stability, comprises a matrix of polyphenylene ether resin and dispersed therein, as stabilizer, a phosphonous acid or esterthereof of the formula wherein R1 represents an alkyl group, an aryl group which may be substituted by an alkyl group, an aralkyl group which may be substituted by an alkyl group, or a group of the formula (a) in which R. groups are identical or different alkyl groups, and R, and R, are identical or different and each represents a hydrogen atom, an alkyl group, an aryl group which may be substituted by an alkyl group, or an aralkyl group which may be substituted by an alkyl group, provided that when R, represents the group of formula (a), R, and R3 represent identical or different 2,4-dialkylphenyl groups.

  一种具有更好热稳定性的聚苯醚树脂组合物，包括聚苯醚树脂基体和分散在其中的 作为稳定剂的磷酸或其酯，其式如下 其中 R1 代表烷基、可被烷基取代的芳基、可被烷基取代的芳烷基或式（a）的基团 其中 R.基团是相同或不同的烷基，且 R，和 R，是相同或不同的，且各自代表氢原子、烷基、可被烷基取代的芳基或可被烷基取代的芳烷基，但当 R 代表式（a）的基团时，R，和 R3 代表相同或不同的 2，4-二烷基苯基。
• Process for the preparation of a hydroxylamine
  申请人：AKZO N.V.

  公开号：EP0147879A1

  公开（公告）日：1985-07-10

  The present invention relates to a process for the preparation of organic hydroxylamines as a result of the corresponding nitroderivative being hydrogenated in the presence of an inert solvent, a platinum catalyst, a nitrogen-containing base (in an amount of less than 10% by weight calculated on the amount of nitro derivative) and a tri- or pentavalent organic phosphorus compound. It has been found that if only use is made of the nitrogen-containing base or the phosphorus compound the yields of isolated hydroxyl amine are significantly reduced in comparison with those obtained with the present process.

  本发明涉及一种制备有机羟胺的工艺，该工艺是相应的硝基衍生物在惰性溶剂、铂催化剂、含氮碱（按硝基衍生物量计算，其用量少于 10%（重量））和三价或五价有机磷化合物存在下氢化的结果。 研究发现，如果仅使用含氮碱或磷化合物，分离出的羟胺的产率与本工艺相比会明显降低。