Ethyl 6-aminopyridazine-4-carboxylate | 916056-75-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: Ethyl 6-aminopyridazine-4-carboxylate
• CAS: 916056-75-2
• 化学式: C₇H₉N₃O₂
• 分子量: 167.17
• InChiKey: RKEGABZBCXABCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  78.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Compositions and methods of treating retinal disease
  申请人：Aldeyra Therapeutics, Inc.

  公开号：US10202348B2

  公开（公告）日：2019-02-12

  Compositions and methods for treating macular degeneration and other forms of retinal disease whose etiology involves the accumulation of A2E and/or lipofuscin, and, more specifically, for preventing the formation and/or accumulation of A2E are disclosed.

  本发明公开了用于治疗黄斑变性和其他形式的视网膜疾病（其病因涉及 A2E 和/或脂褐质的积累）的组合物和方法，更具体地说，是用于防止 A2E 的形成和/或积累的组合物和方法。
• PROTEIN KINASE INHIBITORS (VARIANTS), USE THEREOF IN TREATING ONCOLOGICAL DISEASES AND A PHARMACEUTICAL COMPOSITION BASED THEREON
  申请人：Obshchestvo S Ogranichennoy Otvetstvennostyou "Fusion Pharma"

  公开号：EP2743266B1

  公开（公告）日：2016-08-17
• Compositions and Methods of Treating Retinal Disease
  申请人：Jordan Thomas A.

  公开号：US20110263645A1

  公开（公告）日：2011-10-27

  Compositions and methods for treating macular degeneration and other forms of retinal disease whose etiology involves the accumulation of A2E and/or lipofuscin, and, more specifically, for preventing the formation and/or accumulation of A2E are disclosed
• COMPOSITIONS AND METHODS OF TREATING RETINAL DISEASE
  申请人：ALDEXA THERAPEUTICS, INC.

  公开号：US20150209333A1

  公开（公告）日：2015-07-30

  Compositions and methods for treating macular degeneration and other forms of retinal disease whose etiology involves the accumulation of A2E and/or lipofuscin, and, more specifically, for preventing the formation and/or accumulation of A2E are disclosed.
• US7973025B2
  申请人：——

  公开号：US7973025B2

  公开（公告）日：2011-07-05