(S)-2-[(3S,4R)-2-Oxo-3-phenoxy-4-((E)-styryl)-azetidin-1-yl]-propionic acid | 906644-74-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: (S)-2-[(3S,4R)-2-Oxo-3-phenoxy-4-((E)-styryl)-azetidin-1-yl]-propionic acid
• CAS: 906644-74-4
• 化学式: C₂₀H₁₉NO₄
• 分子量: 337.375
• InChiKey: CFZNSEKVUIAKJN-URKKMRASSA-N

反应信息

• 作为反应物：
  描述：

  (S)-2-[(3S,4R)-2-Oxo-3-phenoxy-4-((E)-styryl)-azetidin-1-yl]-propionic acid 在 四氯化碳 、 草酰氯 、 三苯基膦 作用下， 生成
  参考文献：
  名称：

  Stereoselective synthesis of highly functionalised tricyclic β-lactams via intramolecular nitrilimine cycloaddition

  摘要：

  The novel azeto[2',1':1,2]pyrrolo[3,4-c]pyrazole skeleton has been obtained in both racemic and enantiopure forms by means of intramolecular cycloaddition of nitrilimines 6. Fully stereoselective cycloadditions were obtained, giving tricyclic beta-lactams 7 as single diastereoisomers with good overall yields. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.04.029
• 作为产物：
  描述：

  (S)-2-[(3S,4R)-2-Oxo-3-phenoxy-4-((E)-styryl)-azetidin-1-yl]-propionic acid methyl ester 在 sodium hydroxide 作用下， 以 四氢呋喃 、 水 为溶剂， 以96%的产率得到(S)-2-[(3S,4R)-2-Oxo-3-phenoxy-4-((E)-styryl)-azetidin-1-yl]-propionic acid
  参考文献：
  名称：

  Stereoselective synthesis of highly functionalised tricyclic β-lactams via intramolecular nitrilimine cycloaddition

  摘要：

  The novel azeto[2',1':1,2]pyrrolo[3,4-c]pyrazole skeleton has been obtained in both racemic and enantiopure forms by means of intramolecular cycloaddition of nitrilimines 6. Fully stereoselective cycloadditions were obtained, giving tricyclic beta-lactams 7 as single diastereoisomers with good overall yields. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.04.029