(E)-1-(diphenylphosphinyl)-4-methoxy-1-butene | 1366268-26-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-1-(diphenylphosphinyl)-4-methoxy-1-butene
• CAS: 1366268-26-9
• 化学式: C₁₇H₁₉O₂P
• 分子量: 286.31
• InChiKey: DBGOFRCJMHRMLX-OQLLNIDSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.55
• 重原子数：
  20.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  4-甲氧基丁-1-炔 、 Diphenylphosphine oxide 在 MCM-41-immobilized bidentate phosphine rhodium complex [MCM-41-2P-RhCl(PPh₃)] 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以88%的产率得到(E)-1-(diphenylphosphinyl)-4-methoxy-1-butene
  参考文献：
  名称：

  Highly regio- and stereoselective hydrophosphinylation of acetylenes with diphenylphosphine oxide catalyzed by immobilization of rhodium in MCM-41

  摘要：

  Highly regio- and stereoselective hydrophosphinylation of a wide range of acetylenes with diphenylphosphine oxide was achieved in toluene at 70 degrees C in the presence of 2 mol% of an MCM-41-immobilized bidentate phosphine rhodium complex [MCM-41-2P-RhCl(PPh3)], yielding a variety of (E)-alkenylphosphine oxides in good to excellent yields. This heterogeneous rhodium catalyst can be easily recovered and recycled by a simple filtration of the reaction solution and used for at least 10 consecutive trials without significant loss of activity or selectivity. (C) 2012 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.05.031