1-methoxy-3-pentoxypropan-2-ol | 13021-55-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1-methoxy-3-pentoxypropan-2-ol
• CAS: 13021-55-1
• 化学式: C₉H₂₀O₃
• 分子量: 176.256
• InChiKey: LNUBDWLKRFQOHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Method for producing 3-l-menthoxypropane-1,2-diol
  申请人：Takasago International Corporation

  公开号：US20020156327A1

  公开（公告）日：2002-10-24

  A method for safely and efficiently producing high purity 3-l-menthoxypropane-1,2-diol and intermediates to be used in the method. As shown in the following reaction formula, 3-l-menthoxypropane-1,2-diol represented by the chemical formula (IV) is produced by adding l-menthol to a 1,2-epoxy-3-halogenopropane represented by the general formula (I) (wherein X represents a halogen atom) in an organic solvent in the presence of a Lewis acid, thereby producing a 1-halogeno-3-l-menthoxypropan-2-ol represented by the general formula (II), allowing the first intermediate to react with an alkali metal salt of an aliphatic carboxylic acid having from 1 to 5 carbon atoms to produce a 1-acyloxy-2-substituted-3-l-menthoxypropane represented by the general formula (III) and then hydrolyzing the second intermediate.

  一种安全高效地生产高纯度3-叶酚基丙烷-1,2-二醇及其中间体的方法，用于该方法。如下反应方程所示，通过将叶醇加入到一种1,2-环氧-3-卤代丙烷（通式（I）中X代表卤素原子）的有机溶剂中，在Lewis酸的存在下产生3-叶酚基丙烷-1,2-二醇（化学式（IV）），从而产生1-卤代-3-叶酚基丙烷-2-醇（通式（II）），让第一个中间体与具有1至5个碳原子的脂肪族羧酸的碱金属盐发生反应，产生1-酰氧基-2-取代-3-叶酚基丙烷（通式（III）），然后水解第二个中间体。
• PERFUMES IN THE FORM OF AQUEOUS MICROEMULSIONS
  申请人：CHANEL PARFUMS BEAUTE

  公开号：US20200323749A1

  公开（公告）日：2020-10-15

  Disclosed is a microemulsion of oil-in-water type including, preferably consisting of, by weight relative to the total weight of microemulsion: • 70% to 94% of water, • 1% to 15% of at least one hydrophobic fragrancing substance, • 4% to 20% of at least one preferably volatile solvo-surfactant, and • 0.1% to 15%, preferably 1% to 13%, of at least one hydrotropic agent or at least one surfactant selected from anionic surfactants, cationic surfactants, amphoteric surfactants and non-ionic surfactants. The solvo-surfactant is selected from monoalkylated glycerol derivatives of following formula (I): wherein the “alkyl” group is a linear or branched alkyl group including from 1 to 8 carbon atoms, and R and R′ are each independently H or a linear or branched alkyl group including from 1 to 5 carbon atoms, with the proviso that R is different from R′, and mixtures thereof.

  公开了一种油包水型微乳液，包括，相对于微乳液的总重量，优选包括： • 70%至94%的水， • 1%至15%的至少一种疏水香料物质， • 4%至20%的至少一种优选挥发性溶剂表面活性剂，以及 • 0.1%至15%，优选1%至13%的至少一种增溶剂或至少一种选择自阴离子表面活性剂、阳离子表面活性剂、两性表面活性剂和非离子表面活性剂的表面活性剂。溶剂表面活性剂选择自以下化学式（I）的单烷基甘油衍生物：其中“烷基”基团是包括1至8个碳原子的直链或支链烷基基团，R和R'各自独立地是H或包括1至5个碳原子的直链或支链烷基基团，但R与R'不同，并且它们的混合物。
• Perfumes in the form of aqueous microemulsions
  申请人：CHANEL PARFUMS BEAUTE

  公开号：US11052025B2

  公开（公告）日：2021-07-06

  Disclosed is a microemulsion of oil-in-water type including, preferably consisting of, by weight relative to the total weight of microemulsion: •70% to 94% of water, •1% to 15% of at least one hydrophobic fragrancing substance, •4% to 20% of at least one preferably volatile solvo-surfactant, and •0.1% to 15%, preferably 1% to 13%, of at least one hydrotropic agent or at least one surfactant selected from anionic surfactants, cationic surfactants, amphoteric surfactants and non-ionic surfactants. The solvo-surfactant is selected from monoalkylated glycerol derivatives of following formula (I): wherein the “alkyl” group is a linear or branched alkyl group including from 1 to 8 carbon atoms, and R and R′ are each independently H or a linear or branched alkyl group including from 1 to 5 carbon atoms, with the proviso that R is different from R′, and mixtures thereof.

  本发明公开了一种水包油型微乳液，按相对于微乳液总重量的重量计，该微乳液包括，优选由以下成分组成：-70%至 94%的水、-1%至 15%的至少一种疏水性芳香物质、-4%至 20%的至少一种优选挥发性溶剂表面活性剂，以及-0.1%至 15%，优选 1%至 13%的至少一种亲水剂或至少一种选自阴离子表面活性剂、阳离子表面活性剂、两性表面活性剂和非离子表面活性剂的表面活性剂。溶解表面活性剂选自下式 (I) 的单烷基化甘油衍生物： 其中 "烷基 "是包括 1 至 8 个碳原子的直链或支链烷基，R 和 R′各自独立地为 H 或包括 1 至 5 个碳原子的直链或支链烷基，但 R 与 R′不同，以及它们的混合物。
• PARFUMS SOUS FORME DE MICROÉMULSIONS AQUEUSES
  申请人：Chanel Parfums Beauté

  公开号：EP3463586A1

  公开（公告）日：2019-04-10
• US6515188B2
  申请人：——

  公开号：US6515188B2

  公开（公告）日：2003-02-04