2-(4-tert-butyl-1H-imidazol-1-yl)pyridine | 1261616-72-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(4-tert-butyl-1H-imidazol-1-yl)pyridine
• 英文别名: 2-(4-Tert-butylimidazol-1-yl)pyridine
• CAS: 1261616-72-1
• 化学式: C₁₂H₁₅N₃
• 分子量: 201.271
• InChiKey: NGRDUWLTJGPARQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(4-tert-butyl-1H-imidazol-1-yl)pyridine 、 碘甲烷 以 乙酸乙酯 为溶剂， 反应 38.0h， 以71%的产率得到
  参考文献：
  名称：

  A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

  摘要：

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.059
• 作为产物：
  描述：

  2-溴吡啶 、 5-叔丁基-1H-咪唑 在 copper(l) iodide 、 potassium carbonate 、 L-脯氨酸 作用下， 以 二甲基亚砜 为溶剂， 反应 65.0h， 以36%的产率得到2-(4-tert-butyl-1H-imidazol-1-yl)pyridine
  参考文献：
  名称：

  A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

  摘要：

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.10.059

文献信息

• METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE
  申请人：FUKUZAKI Eiji

  公开号：US20110050093A1

  公开（公告）日：2011-03-03

  To provide methods of forming fluorescence-producing organometallic complexes which can ensure high durability when used in organic electroluminescence devices. For example, a compound 106 is prepared in accordance with the following reaction scheme.
• Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device
  申请人：UDC IRELAND LIMITED

  公开号：US20150311455A1

  公开（公告）日：2015-10-29

  To provide methods of forming fluorescence-producing organometallic complexes which can ensure high durability when used in organic electroluminescence devices. For example, a compound 106 is prepared in accordance with the following reaction scheme.
• US9062084B2
  申请人：——

  公开号：US9062084B2

  公开（公告）日：2015-06-23
• A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation
  作者：Martin Peters、Rolf Breinbauer

  DOI：10.1016/j.tetlet.2010.10.059

  日期：2010.12

  The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported. (C) 2010 Elsevier Ltd. All rights reserved.