1-Ethyl-2-(2-methoxy-phenoxymethyl)-1H-benzoimidazole | 433700-04-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1-Ethyl-2-(2-methoxy-phenoxymethyl)-1H-benzoimidazole
• 英文别名: 1-ethyl-2-[(2-methoxyphenoxy)methyl]benzimidazole
• CAS: 433700-04-0
• 化学式: C₁₇H₁₈N₂O₂
• mdl: MFCD03130091
• 分子量: 282.34
• InChiKey: OBRZBXSLWYFEJS-UHFFFAOYSA-N

物化性质

• 沸点：
  458.6±25.0 °C(Predicted)
• 密度：
  1.14±0.1 g/cm3(Predicted)
• 溶解度：
  41.9 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT
  申请人：Severson Bill

  公开号：US20130085133A1

  公开（公告）日：2013-04-04

  The present disclosure relates to novel compounds of formulas (1) through (19) and to a method for treating humans infected with a virus including various respiratory viruses such as members of the Paramyxoviridae family (respiratory syncytial virus (RSV), human metapneumovirus (HMPV), human parainfluenza virus (HPIV), measles virus, and mumps virus) with a compound of formulas (1) through (19). The present disclosure also relates to a cytopathic effect (CPE)-based assay that will assess virus-induced CPE for screening of compounds for treating viral diseases or inhibiting a virus.