1-(4-{4-[(1-ethyl-pyrrolidin-2-ylmethyl)-amino]-6-phenyl-pyrimidin-2-ylamino}-phenyl)-cyclobutanecarboxylic acid methyl ester | 1215102-76-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-(4-{4-[(1-ethyl-pyrrolidin-2-ylmethyl)-amino]-6-phenyl-pyrimidin-2-ylamino}-phenyl)-cyclobutanecarboxylic acid methyl ester
• 英文别名: Methyl 1-[4-[[4-[(1-ethylpyrrolidin-2-yl)methylamino]-6-phenylpyrimidin-2-yl]amino]phenyl]cyclobutane-1-carboxylate
• CAS: 1215102-76-3
• 化学式: C₂₉H₃₅N₅O₂
• 分子量: 485.629
• InChiKey: SPFJOTGWZGGKFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  36
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  79.4
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS
  申请人：Alexander Christopher W.

  公开号：US20100144722A1

  公开（公告）日：2010-06-10

  Novel heterocyclic compounds, sstereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. Additionally, methods of forming novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided.

  提供了式(I)及其立体异构体和/或药学上可接受的盐的新型杂环化合物。此外，还提供了形成新型杂环化合物、其立体异构体和/或药学上可接受的盐的方法。
• [EN] HETEROCYCLIC COMPOUNDS AS GATA MODULATORS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES COMME MODULATEURS DE GATA
  申请人：REDDYS LAB LTD DR

  公开号：WO2010028179A1

  公开（公告）日：2010-03-11

  Novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. Additionally, methods of forming novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided.