4'-tert-butyl 4-methyl stilbene | 156871-47-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4'-tert-butyl 4-methyl stilbene
• 英文别名: 1-(tert-butyl)-4-(4-methylstyryl)benzene；1-Tert-butyl-4-[2-(4-methylphenyl)ethenyl]benzene
• CAS: 156871-47-5
• 化学式: C₁₉H₂₂
• 分子量: 250.384
• InChiKey: MVGWJGLKGGPGGC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4'-tert-butyl 4-methyl stilbene 在 N-溴代丁二酰亚胺(NBS) 、 碘 、 过氧化苯甲酰 作用下， 以 四氯化碳 、 环己烷 为溶剂， 反应 33.0h， 生成
  参考文献：
  名称：

  Corannulene-Helicene杂种：同时包含碗形和螺旋形的手性π系统

  摘要：

  使π系统呈非平面的两个不同的结构元素，即测地曲率和螺旋图案，已被组合为包含两个特征的新聚芳烃。所得的Corannulene– [ n ]螺旋烯（n = 5、6）在其对映异构过程中显示出独特的分子动力学，包括碗形和螺旋形的反转运动。还首次获得了基于Corannulene的骨架手性分子的光学拆分，并研究了碗基序环化对手性的影响。

  DOI：

  10.1021/acs.orglett.6b01801
• 作为产物：
  描述：

  对溴甲苯 、 4-叔丁基苯乙烯 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以90%的产率得到4'-tert-butyl 4-methyl stilbene
  参考文献：
  名称：

  In situ synthesis of a Pd–poly (1,8-diaminonaphthalene) nanocomposite: An efficient catalyst for Heck reactions under phosphine-free conditions

  摘要：

  Polymerization of 1 8-diaminonaphthalene was performed using palladium acetate as an oxidizing agent During the oxidative polymerization process the electrons liberated reduced the palladium (II) ions with the formation Pd nanoparticles these colloidal particles being stabilized within the poly (1 8 diaminonaphthalene) matrix Electron microscope images revealed that the palladium particles were well dispersed in the polymer matrix and had an average diameter of 2 5 nm The metal-polymer composite material was initially tested for the coupling of iodobenzene with alkene (methyl acrylate) in the presence of a base The yield of the substituted alkene derivative was found to be excellent A series of iodo- and bromobenzene derivatives were tested for the coupling reaction with different alkenes A coupled product was produced with high TOF values proving the efficiency of the composite material as an efficient catalyst for the Heck reaction under phosphine-free conditions (C) 2010 Elsevier B V All rights reserved

  DOI：

  10.1016/j.catcom.2010.08.005

文献信息

• Synthesis of Water-Dispersible Pd Nanoparticles Using a Novel Oxacalixarene Derivative and their Catalytic Application in C–C Coupling Reactions
  作者：Viren Mehta、Manthan Panchal、Anita Kongor、Urvi Panchal、V. K. Jain

  DOI：10.1007/s10562-016-1781-y

  日期：2016.8

  and characterized using various spectroscopic techniques. This DHOC derivative has been used to produce water-dispersible catalytically active Pd nanoparticles (PdNps). In the nanoparticle synthesis, DHOC serves as both a reducing and a stabilizing agent, thus simplifying the preparation of the PdNps because no separate reagents are required to reduce and stabilize the nanoparticles. These PdNps were

  一种新型 5,17-di(hydrazinecarbonyl) tetranitrooxacalix [4] 芳烃 (DHOC) 衍生物已合成并使用各种光谱技术进行表征。这种 DHOC 衍生物已用于生产水分散性催化活性 Pd 纳米粒子 (PdNps)。在纳米粒子合成中，DHOC 既是还原剂又是稳定剂，因此简化了 PdNps 的制备，因为不需要单独的试剂来还原和稳定纳米粒子。这些 PdNps 通过多种技术进行表征，例如透射电子显微镜和紫外-可见光谱。水分散性 PdNps 的大小为 5 ± 2 nm，并在许多 C-C 偶联反应中显示出高催化活性，例如 Sonogashira、Suzuki-Miyuara 和 Heck 反应。图形摘要
• Palladium polyether diphosphinite complex anchored in polyethylene glycol as an efficient homogeneous recyclable catalyst for the Heck reactions
  作者：Dinesh Sawant、Yogesh Wagh、Kushal Bhatte、Anil Panda、Bhalchandra Bhanage

  DOI：10.1016/j.tetlet.2011.02.100

  日期：2011.5

  Palladium polyether diphosphinite complex anchored on polyethylene glycol is reported as an efficient catalyst for Heck coupling reactions. The catalyst is soluble in the solvent with reactants and products during reaction and can be separated from reaction media in biphasic form by the addition of anti-solvent like n-hexane and further recycled. The developed methodology offers mild reaction condition

  据报道，锚定在聚乙二醇上的聚醚二亚膦酸钯复合物是用于Heck偶联反应的有效催化剂。的催化剂是反应过程中可溶于与反应物和产物的溶剂，并且可以从反应介质中的两相的形式通过添加等反溶剂的分离ñ -己烷和进一步回收。所开发的方法提供了温和的反应条件，较短的反应时间以及优异的催化剂可回收性。芳基碘化物和芳基溴化物具有良好的耐受性，可提供出色的收率。
• Controlled synthesis of uniform palladium nanoparticles on novel micro-porous carbon as a recyclable heterogeneous catalyst for the Heck reaction
  作者：Kunpeng Song、Peng Liu、Jingyu Wang、Lei Pang、Jian Chen、Irshad Hussain、Bien Tan、Tao Li

  DOI：10.1039/c5dt02133b

  日期：——

  Highly dispersed palladium nanoparticles encaged by micro-porous carbon exhibit excellent cycling performance towards the Heck cross-coupling reaction.

  高度分散的钯纳米颗粒被微孔碳包裹，对Heck交叉偶联反应表现出优秀的循环性能。
• Pd immobilized on EDTA-modified cellulose: synthesis, characterization, and catalytic application in inter- and intramolecular Heck reactions and Larock reactions
  作者：Zhian Xu、Jinxi Xu、Yuping Zhou、Yuling Huang、Yiqun Li

  DOI：10.1007/s11164-022-04766-x

  日期：2022.8

  regulation of multidentate sites of EDTA, the immobilized Pd exhibited high catalytic activity in the inter- and intramolecular Heck reactions and heteroannulation Larock reactions to afford the desired products in excellent yields (66–97%). The catalyst recycling experiments for the model Heck reaction showed that the catalyst can be reused at least four consecutive runs with a slight drop in its catalytic

  通过用乙二胺四乙酸（EDTA）二酐对纤维素进行酯化和用PdCl 2复分解的顺序程序，成功地制备了固定在EDTA改性纤维素上的Pd（Pd@Cell-EDTA）. 通过 ICP-AES、FTIR、SEM、EDX、元素映射、TEM 和 XPS 工具对合成后的 Pd@Cell-EDTA 进行了很好的表征。TEM显示球形Pd纳米颗粒均匀分散在Cell-EDTA表面，粒径约为5 nm，ICP-AES测定新鲜Pd@Cell-EDTA催化剂中Pd含量为0.10 mmol/g。由于 EDTA 多齿位点的调节，固定化的 Pd 在分子间和分子内 Heck 反应和异环化 Larock 反应中表现出高催化活性，以优异的产率 (66-97%) 提供所需的产物。模型 Heck 反应的催化剂回收实验表明，催化剂可以至少连续重复使用四次，但其催化活性略有下降。 图形概要
• Synthesis and calcium antagonistic activity of diethyl styrylbenzylphosphonates
  作者：S Younes、G Tchani、G Baziard-Mouysset、JL Stigliani、M Payard、R Bonnafous、J Tisne-Versailles

  DOI：10.1016/0223-5234(94)90204-6

  日期：1994.1

  Twenty-three new phosphonic ester derivatives of stilbene exhibiting structural analogies with fostedil are described. Examination of calcium antagonism showed that this activity could not be increased by introducing electron-withdrawing, electron-releasing or lipophilic substituents. Only compounds containing fluorine at the 2 or 4 positions exhibited similar activity to the model.