2-fluro 4'-methyl stilbene | 156871-43-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2-fluro 4'-methyl stilbene
• 英文别名: 1-Fluoro-2-[2-(4-methylphenyl)ethenyl]benzene
• CAS: 156871-43-1
• 化学式: C₁₅H₁₃F
• 分子量: 212.267
• InChiKey: BDKFDCFAMHRCPG-UHFFFAOYSA-N

物化性质

• 沸点：
  306.4±22.0 °C(Predicted)
• 密度：
  1.099±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-fluro 4'-methyl stilbene 在 potassium sulfide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以92%的产率得到2-(4-methylphenyl)benzo[b]thiophene
  参考文献：
  名称：

  Transition-Metal-Free Method for the Synthesis of Benzo[b]thiophenes from o-Halovinylbenzenes and K2S via Direct SNAr-Type Reaction, Cyclization, and Dehydrogenation Process

  摘要：

  A new, highly efficient procedure for the synthesis of benzothiophenes from easily available o-halovinylbenzenes and potassium sulfide has been developed. The reaction tolerated a wide range of functionalities, and various 2-substituted benzo[b]thiophenes are provided in the high yields in the absence of a transition-metal catalyst.

  DOI：

  10.1055/s-0033-1339289
• 作为产物：
  描述：

  2-氟溴苄 在 potassium tert-butylate 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 11.0h， 生成 2-fluro 4'-methyl stilbene
  参考文献：
  名称：

  Transition-Metal-Free Method for the Synthesis of Benzo[b]thiophenes from o-Halovinylbenzenes and K2S via Direct SNAr-Type Reaction, Cyclization, and Dehydrogenation Process

  摘要：

  A new, highly efficient procedure for the synthesis of benzothiophenes from easily available o-halovinylbenzenes and potassium sulfide has been developed. The reaction tolerated a wide range of functionalities, and various 2-substituted benzo[b]thiophenes are provided in the high yields in the absence of a transition-metal catalyst.

  DOI：

  10.1055/s-0033-1339289

文献信息

• Synthesis and calcium antagonistic activity of diethyl styrylbenzylphosphonates
  作者：S Younes、G Tchani、G Baziard-Mouysset、JL Stigliani、M Payard、R Bonnafous、J Tisne-Versailles

  DOI：10.1016/0223-5234(94)90204-6

  日期：1994.1

  Twenty-three new phosphonic ester derivatives of stilbene exhibiting structural analogies with fostedil are described. Examination of calcium antagonism showed that this activity could not be increased by introducing electron-withdrawing, electron-releasing or lipophilic substituents. Only compounds containing fluorine at the 2 or 4 positions exhibited similar activity to the model.
• Expeditious synthesis of fluorinated styrylbenzenes and polyaromatic hydrocarbons
  作者：Ashutosh V. Bedekar、Anju R. Chaudhary、M. Shyam Sundar、Murali Rajappa

  DOI：10.1016/j.tetlet.2012.11.022

  日期：2013.1

  A series of fluorinated styrylbenzene derivatives were synthesized by the Mizoroki-Heck reaction using phosphine-free catalytic conditions or by adopting the one-pot Wittig-Heck reaction sequence. The fluorinated styrylbenzenes were converted into polyaromatic hydrocarbons such as phenanthrenes, [4]helicenes, and benzo[ghi]perylene by a modified photocyclization procedure involving I-2-THF condition. (C) 2012 Elsevier Ltd. All rights reserved.
• PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME
  申请人：TOSOH CORPORATION

  公开号：US20210135115A1

  公开（公告）日：2021-05-06

  Provided is a resin which is excellent in terms of solubility in common solvents, crosslinking temperature, time required for crosslinking, solvent resistance (cracking resistance), breakdown voltage, leakage current, solvent wettability, and planarity in cases where the resin is formed into a thin film. A resin which comprises repeating units represented by formula (1) and formula (2), and wherein the repeating unit represented by formula (2) is contained in an amount of 20% by mole or more relative to the total amount of the repeating units represented by formula (1) and formula (2).