| 1169606-02-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1169606-02-3
• 化学式: C₂₈H₂₂Cl₂FNO₄S₂
• 分子量: 590.523
• InChiKey: IEMRKZNRYCLEMO-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  N-氟代双苯磺酰胺 、 di(4-chlorophenyl)methylenecyclopropane 以 四氢呋喃 为溶剂， 反应 24.0h， 以62%的产率得到
  参考文献：
  名称：

  Reactions of methylenecyclopropanes and vinylidenecyclopropanes with N-fluorodibenzenesulfonimide

  摘要：

  Methylenecyclopropanes and vinylidenecyclopropanes undergo ring-opening reactions with N-fluoroclibenzenesulfonimide (NFSI) upon heating at 60 degrees C in tetrahydrofuran to give the corresponding fluorinated derivatives 2 and 6 in good to excellent yields. A plausible reaction mechanism has been discussed on the basis of previous literature. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.04.075

文献信息

• Stereoselective fluorination of methylenecyclopropanes with N-F reagents: A modular entry to γ-fluorohomoallylic sulfonimides and γ-fluorohomoallylic amides
  作者：Weijun Fu、Guanglong Zou、Mei Zhu、Dongfeng Hong、Dongsheng Deng、Chen Xun、Baoming Ji

  DOI：10.1016/j.jfluchem.2009.07.020

  日期：2009.11

  A convenient and efficient method for fluorination of methylenecyclopropanes is reported. This is exemplified in the stereoselective preparation of N-[(E)-3-fluorobut-3-en-1-yl]-benzenesulfonimides by the reaction of methylenecyclopropanes with N-fluorobenzenesulfonimide in good to excellent yields. Moreover, gamma-fluorohomoallylic amides are synthesized using Selectfluor in R3CN at 60 degrees C. (C) 2009 Elsevier B.V. All rights reserved.