1-(6-Bromopyridin-2-YL)cyclopropan-1-amine | 1060811-33-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(6-Bromopyridin-2-YL)cyclopropan-1-amine
• CAS: 1060811-33-7
• 化学式: C₈H₉BrN₂
• 分子量: 213.07
• InChiKey: BAEAFXDAFMBZRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  38.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  乙基溴化镁 、 2-溴-6-氰基吡啶 以 四氢呋喃 为溶剂， 生成 1-(6-Bromopyridin-2-YL)cyclopropan-1-amine
  参考文献：
  名称：

  TRICYCLIC COMPOUNDS

  摘要：

  The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for treating diseases such as cancer.

  公开号：

  WO2024107393A1

文献信息

• TRICYCLIC COMPOUNDS
  申请人：[en]SCHRÖDINGER, INC.

  公开号：WO2024107393A1

  公开（公告）日：2024-05-23

  The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for treating diseases such as cancer.