triphenyllead magnesium bromide | 64362-17-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: triphenyllead magnesium bromide
• CAS: 64362-17-0
• 化学式: C₁₈H₁₅BrMgPb
• 分子量: 542.726
• InChiKey: ZQMBANPLAIOUHM-UHFFFAOYSA-M

反应信息

• 作为反应物：
  描述：

  triphenyllead magnesium bromide 、 3-溴丙炔 以 四氢呋喃 、 甲苯 为溶剂， 以75-80的产率得到Propadienyl-triphenylplumban
  参考文献：
  名称：

  三苯基烯丙基铅：一种简便的制备方法及其作为炔丙基化试剂的用途

  摘要：

  Triphenylallenyllead, which is easily prepared by reaction of the readily available Ph3PbMgBr (in situ, via 3 PhMgBr + PbCl2 in THF) with propargyl bromide, reacts with aldehydes in the presence of a Lewis acid (BF3.OEt2 or TiCl4) to give homopropargylic alcohols, RCH(OH)CH2C=CH, in good yield. Propargylation of ketones requires transmetalation of Ph3PbCH=C=CH2 with PhLi to CH2=C=CHLi and reaction of the latter with the ketone.

  DOI：

  10.1021/om00017a081
• 作为产物：
  描述：

  苯基溴化镁 、 lead(II) chloride 以 四氢呋喃 为溶剂， 生成 triphenyllead magnesium bromide
  参考文献：
  名称：

  三苯基烯丙基铅：一种简便的制备方法及其作为炔丙基化试剂的用途

  摘要：

  Triphenylallenyllead, which is easily prepared by reaction of the readily available Ph3PbMgBr (in situ, via 3 PhMgBr + PbCl2 in THF) with propargyl bromide, reacts with aldehydes in the presence of a Lewis acid (BF3.OEt2 or TiCl4) to give homopropargylic alcohols, RCH(OH)CH2C=CH, in good yield. Propargylation of ketones requires transmetalation of Ph3PbCH=C=CH2 with PhLi to CH2=C=CHLi and reaction of the latter with the ketone.

  DOI：

  10.1021/om00017a081