(1S,2R)-1-Bromomethyl-2-(2-bromo-propyl)-cyclohexane | 137303-31-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 英文名称: (1S,2R)-1-Bromomethyl-2-(2-bromo-propyl)-cyclohexane
• CAS: 137303-31-2
• 化学式: C₁₀H₁₈Br₂
• 分子量: 298.061
• InChiKey: LIJGMAVDUMSSBM-VXRWAFEHSA-N

反应信息

• 作为反应物：
  描述：

  (1S,2R)-1-Bromomethyl-2-(2-bromo-propyl)-cyclohexane 在 potassium sulfide 作用下， 以 乙醇 为溶剂， 生成 (1S,3aS,7aS)-1-Ethyl-octahydro-benzo[c]thiophene 、 (1R,3aS,7aS)-1-Ethyl-octahydro-benzo[c]thiophene 、 trans-3-methyl-trans-2-thiadecalin 、 trans-3-methyl-trans-2-thiadecalin
  参考文献：
  名称：

  Synthesis of 1-substituted trans-2-thiahydrindanes and 3-substituted trans-2-thiadecalins

  摘要：

  Methods of synthesis of 1-R-trans-2-thiahydrindanes and 3-R-trans-2-thiadecalins from trans-1-methoxymethyl-2-chlorocyclohexane have been developed. The order of the chromatographic elution of the isomeric sulfides formed has been found. The configurations of the compounds have been established by H-1 and C-13 NMR spectroscopy. The characteristics of the intermediate and final compounds are given. The splitting of 1-R-trans-2-oxahydrindanes and 3-R-trans-2-oxadecalins by the PBr3/conc. HBr system has been effected.

  DOI：

  10.1007/bf01172271
• 作为产物：
  描述：

  (4aR,8aS)-3-Methyl-octahydro-isochromene 在 氢溴酸 、 三溴化磷 作用下， 以80%的产率得到(1S,2R)-1-Bromomethyl-2-(2-bromo-propyl)-cyclohexane
  参考文献：
  名称：

  Synthesis of 1-substituted trans-2-thiahydrindanes and 3-substituted trans-2-thiadecalins

  摘要：

  Methods of synthesis of 1-R-trans-2-thiahydrindanes and 3-R-trans-2-thiadecalins from trans-1-methoxymethyl-2-chlorocyclohexane have been developed. The order of the chromatographic elution of the isomeric sulfides formed has been found. The configurations of the compounds have been established by H-1 and C-13 NMR spectroscopy. The characteristics of the intermediate and final compounds are given. The splitting of 1-R-trans-2-oxahydrindanes and 3-R-trans-2-oxadecalins by the PBr3/conc. HBr system has been effected.

  DOI：

  10.1007/bf01172271