9,12,15,18,21,24-hexaoxa-5,28-diaza-tricyclo[24.4.0.0^2,7]triaconta-1(30),2,4,6,26,28-hexaene-8,25-dione | 131366-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 9,12,15,18,21,24-hexaoxa-5,28-diaza-tricyclo[24.4.0.0^2,7]triaconta-1(30),2,4,6,26,28-hexaene-8,25-dione
• 英文别名: 9,12,15,18,21,24-Hexaoxa-5,28-diazatricyclo[24.4.0.02,7]triaconta-1(26),2(7),3,5,27,29-hexaene-8,25-dione
• CAS: 131366-95-5
• 化学式: C₂₂H₂₆N₂O₈
• 分子量: 446.457
• InChiKey: NUKPXHDWCYTAIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  32
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  115
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  1,3-丙烷磺内酯 、 9,12,15,18,21,24-hexaoxa-5,28-diaza-tricyclo[24.4.0.0^2,7]triaconta-1(30),2,4,6,26,28-hexaene-8,25-dione 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 以87%的产率得到5,28-di(3-sulfonatopropyl)-9,12,15,18,21,24-hexaoxa-5,28-diazonia-tricyclo[24.4.0.0^2,7]triaconta-1(30),2,4,6,26,28-hexaene-8,25-dione
  参考文献：
  名称：

  Synthesis of Crown-Ester-Bipyridines and Crown-Ester-Viologens

  摘要：

  Six novel 4,4'-bipyridine-crown-esters, derived from [4,4']bipyridinyl-3,3'-dicarboxylic acid, [4,4']bipyridinyl-2,2'-dicarboxylic acid and [4,4']bipyridinyl-2,2',6,6'-tetra-carboxylic acid were synthesized employing a procedure closely related to the 'cesium carbonate method'. The 4,4'-bipyridine-crown-esters differ in their substitution positions of the aromatic bipyridine-units, as well as in the geometric extensions of their crown-ester moieties. Addition of 1,3-propane sultone to the 4,4'-bipyridine-crown-esters resulted in five novel propanesultonated 4,4'-bipyridine-crown-esteiviologens.

  DOI：

  10.1055/s-2005-861829
• 作为产物：
  描述：

  4-溴-3-甲基吡啶 在 barium dihydroxide 、 potassium permanganate 、 苄基三乙基氯化铵 、 三苯基膦 、 nickel dichloride 、 锌 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 146.0h， 生成 9,12,15,18,21,24-hexaoxa-5,28-diaza-tricyclo[24.4.0.0^2,7]triaconta-1(30),2,4,6,26,28-hexaene-8,25-dione
  参考文献：
  名称：

  Synthesis of Crown-Ester-Bipyridines and Crown-Ester-Viologens

  摘要：

  Six novel 4,4'-bipyridine-crown-esters, derived from [4,4']bipyridinyl-3,3'-dicarboxylic acid, [4,4']bipyridinyl-2,2'-dicarboxylic acid and [4,4']bipyridinyl-2,2',6,6'-tetra-carboxylic acid were synthesized employing a procedure closely related to the 'cesium carbonate method'. The 4,4'-bipyridine-crown-esters differ in their substitution positions of the aromatic bipyridine-units, as well as in the geometric extensions of their crown-ester moieties. Addition of 1,3-propane sultone to the 4,4'-bipyridine-crown-esters resulted in five novel propanesultonated 4,4'-bipyridine-crown-esteiviologens.

  DOI：

  10.1055/s-2005-861829

文献信息

• Duerr, Heinz; Kilburg, Heike; Bossmann, Stefan, Synthesis, 1990, # 9, p. 773 - 778
  作者：Duerr, Heinz、Kilburg, Heike、Bossmann, Stefan

  DOI：——

  日期：——
• DURR, HEINZ;KILBURG, HEIKE;BOSSMANN, STEFAN, SYNTHESIS,(1990) N, C. 773-778
  作者：DURR, HEINZ、KILBURG, HEIKE、BOSSMANN, STEFAN

  DOI：——

  日期：——