butyl 2-[6-bromo-1-(4-methylphenyl)sulfonyl-2H-benzo[cd]indol-2-yl]acetate | 1338495-66-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: butyl 2-[6-bromo-1-(4-methylphenyl)sulfonyl-2H-benzo[cd]indol-2-yl]acetate
• CAS: 1338495-66-1
• 化学式: C₂₄H₂₄BrNO₄S
• 分子量: 502.429
• InChiKey: ZGFJHYWKCKNUCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-溴-1-萘胺 在 吡啶 、 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 copper diacetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 28.0h， 生成 butyl 2-[6-bromo-1-(4-methylphenyl)sulfonyl-2H-benzo[cd]indol-2-yl]acetate
  参考文献：
  名称：

  Rh(III)-Catalyzed Oxidative Olefination of N-(1-Naphthyl)sulfonamides Using Activated and Unactivated Alkenes

  摘要：

  Rhodium(III)-catalyzed oxidative olefination of N-(1-naphthyl)sulfonamides has been achieved at the peri position. Three categories of olefins have been successfully applied. Activated olefins reacted to afford five-membered azacycles as a result of oxidative olefination-hydroamination. Unactivated olefins reacted to give the olefination product. 2-fold oxidative C-C and C-N coupling was achieved for allylbenzenes.

  DOI：

  10.1021/ol2023856

文献信息

• Rh(III)-Catalyzed Oxidative Olefination of <i>N</i>-(1-Naphthyl)sulfonamides Using Activated and Unactivated Alkenes
  作者：Xuting Li、Xue Gong、Miao Zhao、Guoyong Song、Jian Deng、Xingwei Li

  DOI：10.1021/ol2023856

  日期：2011.11.4

  Rhodium(III)-catalyzed oxidative olefination of N-(1-naphthyl)sulfonamides has been achieved at the peri position. Three categories of olefins have been successfully applied. Activated olefins reacted to afford five-membered azacycles as a result of oxidative olefination-hydroamination. Unactivated olefins reacted to give the olefination product. 2-fold oxidative C-C and C-N coupling was achieved for allylbenzenes.