6-Hydroxy-1,5-bis(4-methylphenyl)-6-propyl-1,3,5-triazinane-2,4-dithione | 1346658-98-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-Hydroxy-1,5-bis(4-methylphenyl)-6-propyl-1,3,5-triazinane-2,4-dithione
• CAS: 1346658-98-7
• 化学式: C₂₀H₂₃N₃OS₂
• 分子量: 385.554
• InChiKey: JVXMYTAGKWLVGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  103
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对甲苯基硫脲 、 丁酸 在 iron(III) chloride hexahydrate 作用下， 反应 2.0h， 以90%的产率得到6-Hydroxy-1,5-bis(4-methylphenyl)-6-propyl-1,3,5-triazinane-2,4-dithione
  参考文献：
  名称：

  A concise synthetic method for 1,3,5-triazinane-2,4-dithiones

  摘要：

  1,3,5-Triazinane-2,4-dithiones were efficiently synthesized via condensation of 2 equiv. of 1-arylthioureas with 1 equiv. of aliphatic carboxylic acids using ferric chloride hexahydrate as a catalyst. This protocol has the advantages of high yield, mild condition and simple procedure.

  DOI：

  10.1590/s0103-50532011001000015

文献信息

• A concise synthetic method for 1,3,5-triazinane-2,4-dithiones
  作者：Zheng Li、Hongfang Cai、Jingya Yang、Pengxian Niu、Chenhui Liu

  DOI：10.1590/s0103-50532011001000015

  日期：——

  1,3,5-Triazinane-2,4-dithiones were efficiently synthesized via condensation of 2 equiv. of 1-arylthioureas with 1 equiv. of aliphatic carboxylic acids using ferric chloride hexahydrate as a catalyst. This protocol has the advantages of high yield, mild condition and simple procedure.