N-{3-[4-(2-methoxy-pyridin-3-yl)-pyrimidin-2-ylamino]-phenyl}-acetamide | 1035944-75-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-{3-[4-(2-methoxy-pyridin-3-yl)-pyrimidin-2-ylamino]-phenyl}-acetamide
• 英文别名: N-[3-[[4-(2-methoxypyridin-3-yl)pyrimidin-2-yl]amino]phenyl]acetamide
• CAS: 1035944-75-2
• 化学式: C₁₈H₁₇N₅O₂
• 分子量: 335.365
• InChiKey: MDVBSGNLAATVJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  89
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Organic Compounds and Their Uses
  申请人：Beckwith Rohan Eric John

  公开号：US20100048597A1

  公开（公告）日：2010-02-25

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases.

  本申请描述了有机化合物，可用于治疗、预防和/或缓解疾病。
• FUSED BENZENE DERIVATIVE AND USE
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP1553074B1

  公开（公告）日：2014-06-18
• Fused benzene derivative and use
  申请人：Shiraishi Mitsuru

  公开号：US20060106067A1

  公开（公告）日：2006-05-18

  The present invention provides a compound represented by the general formula: [wherein Ring A represents an optionally substituted 5- to 8-membered ring, Ring B represents a further optionally substituted 4- to 10-membered ring, Ring C represents a further optionally substituted benzene ring, X 1 represents carbon atom, X 2 represents a carbon atom, an oxygen atom, etc., W represents a nitrogen atom, etc., Y 11 represents a group represented by the formula CR 2 R 3′ (wherein R 2 represents a hydrogen atom, a cyano group, a nitro group, etc., and R 3′ represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), Y 21 represents a group represented by the formula CR 4 R 5′ (wherein R 4 represents a hydrogen atom, a cyano group, a nitro group, etc., and R 5′ represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), etc., and R 1 represents an electron-withdrawing group, respectively. The formula represents a single bond or a double bond] or a salt thereof, which is useful as an androgen receptor modulator.
• US7649001B2
  申请人：——

  公开号：US7649001B2

  公开（公告）日：2010-01-19
• [EN] ORGANIC COMPOUNDS AND THEIR USES<br/>[FR] COMPOSÉS ORGANIQUES ET LEURS UTILISATIONS
  申请人：NOVARTIS AG

  公开号：WO2008079933A2

  公开（公告）日：2008-07-03

  [EN] The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases.
  [FR] L'invention concerne des composés organiques utiles pour le traitement, la prévention et/ou l'amélioration de pathologies.