N-Benzolsulfenyl-S,S-dimethylsulfoximid | 30511-02-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-Benzolsulfenyl-S,S-dimethylsulfoximid
• 英文别名: S,S-dimethyl-N-(phenylthio)sulfoximine
• CAS: 30511-02-5
• 化学式: C₈H₁₁NOS₂
• 分子量: 201.313
• InChiKey: QTLLXUHUJUVLDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.42
• 重原子数：
  12.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  29.43
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  苯硫酚 在 h-BN(at)γ-CD(at)Cu(OAc)₂ 作用下， 以 乙醇 、 水 、 甲苯 为溶剂， 反应 36.75h， 生成 N-Benzolsulfenyl-S,S-dimethylsulfoximid
  参考文献：
  名称：

  h-BN@Copper(II) nanomaterial catalyzed cross-coupling reactions between sulfoximines and N-(phenylthio)-succinimide under mild condition

  摘要：

  A novel and efficient method for the synthesis of N-S substituted sulfoximines has been established with h-BN-supported copper(II) nanomaterial as the catalyst. Catalyzed by this heterogeneous catalyst, the desired products were obtained with wide scope of substrates, good to excellent yields, free ligand and low-toxicity solvent. Moreover, after being reused ten times, there is almost no significant loss of its catalytic activity.

  DOI：

  10.1016/j.catcom.2018.04.021

文献信息

• A One-Pot Cascade Reaction by Combining NH-Sulfoximines with Thiophenols Under Mild Conditions
  作者：Yao Peng、Yan Lin、Ruifang Nie、Yang Zheng、Yanzhao Liu、Li Guo、Yong Wu

  DOI：10.1002/ejoc.201701643

  日期：2018.2.14

  We have developed a one‐pot cascade N–S bond formation reaction of free NH‐sulfoximines with thiophenols to produce diverse N‐sulfenyl sulfoximines in moderate to excellent yields. This reaction provides a straightforward, practical way to prepare N‐sulfenyl sulfoximine derivatives

  我们已经开发出了一个单锅级联的游离NH-亚磺酰亚胺与硫酚的N-S键形成反应，从而以中等到极好的收率生产了各种N-亚磺酰基亚砜。该反应提供了一种直接，实用的方法来制备N-亚磺酰基亚砜亚胺衍生物