Pd(butyldiisopropylphosphine)3 | 148508-76-3

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: Pd(butyldiisopropylphosphine)3
• 英文别名: butyl-di(propan-2-yl)phosphane;palladium
• CAS: 148508-76-3
• 化学式: C₃₀H₆₉P₃Pd
• 分子量: 629.219
• InChiKey: DWEURUQPULUQDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.25
• 重原子数：
  34
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  Pd(butyldiisopropylphosphine)3 在 氯苯 作用下， 以 1,4-二氧六环 为溶剂， 以79%的产率得到trans-(butyldiisopropylphosphine)2Pd(C6H5)Cl
  参考文献：
  名称：

  电子丰富的芳基钯配合物与烯烃的反应。乙烯基化催化中螯合作用的起源

  摘要：

  Reaction of (dippp)Pd(Ph)Cl(1) with norbornene or styrene yields (dippp)PdCl2 (8) and (dippp)Pd(eta(2)-olefin). Kinetic follow-up reveals fast formation of (dippp)Pd(phenylnorbornyl)Cl (10), followed by its slow decomposition, with k(insertion) = 0.50 x 10(-3) L mol(-1) s(-1) and k(decomposition) = 0.90 X 10(-4) S-1. Phenylnorbornane and (with styrene) stilbenes are also formed. Faster reaction is observed with (dppp)Pd(Ph)Br (2) and faster still with (dippe)Pd(Cl (4) to yield, in the latter case, the stable (dippe)Pd(phenylnorbornyl)Cl (18). The rates of these reactions are strongly solvent dependent (DMF >> dioxane), are strongly retarded by added Cl-, and are unaffected by added phosphine, indicating that halide dissociation, followed by olefin coordination and rate-determining olefin insertion, are involved. In contrast, reaction of trans-(P(i)Pr(2)(n)Bu)(2)Pd(Ph)X (X = Cl, 5; X = Br, 6) with norbornene (or styrene) involves phosphine dissociation and leads to formation of (P(i)Pr(2)(n)Bu)(2)Pd(H)X. In the case of norbornene, beta-carbon elimination of the unobserved intermediate phenylnorbornyl complexes followed by beta-H elimination yields 1-methylene-2-phenylcyclohexenes. Complexes of the ligand dippb are unique in that both eta(1) and eta(2) coordination modes are easily accessible. While reaction products are similar to those obtained with dippp and dippe complexes, dependence of the reaction rate on reaction variables is intermediate between those observed for complexes of chelating and monodentate phosphines. The implications of these findings on catalysis are outlined.

  DOI：

  10.1021/om00021a021
• 作为产物：
  描述：

  (2-methylallyl)palladium-chloride dimer 、 ⁿBuⁱPr₂P 在 NaOH 作用下， 以 甲醇 、 甲苯 为溶剂， 生成 Pd(butyldiisopropylphosphine)3
  参考文献：
  名称：

  螯合剂对富电子钯配合物的结构和反应性的影响及其与催化作用的关系

  摘要：

  In order to clarify the origin of the ''chelate effect' in catalysis by palladium, complexes of (Pr2P(CH2)nPr2P)-Pr-i-Pr-i (n = 2, dippe; n = 3, dippp; n = 4, dippb), Ph2P(CH2)3PPh2 (dppp), and PiPr2 nBu were prepared and their structures, dynamic properties, and reactivities were compared. Pd(dippe)2 1d is a coordinatively saturated complex, both in solution and in the solid state. X-ray characterization exhibits a distorted tetrahedral geometry. The dippe bite angle is 87.05-degrees. The compound crystallizes in the orthorhombic space group Pnna with a = 16.713(3) angstrom, b = 17.561(3) angstrom, c = 11.116(2) angstrom, V = 3277(1) angstrom3, Z = 4. Pd(dippp)2 (1a) and Pd(dippb)2 (1e) are coordinatively unsaturated, trigonal complexes and are in equilibrium with the binuclear complexes LPd(eta2-L)PdL, 1b and 1f, respectively. Whereas 1d does not exhibit dynamic behavior, 1a and 1e undergo fast, intramolecular phosphine exchange, a process which is not observed with 1b and 1f. The trigonal complexes (dippp)PdPiPr2Bu (1c) and (PiPr2nBu)3Pd were also prepared for comparison. The dippp complexes 1a-1c react with aryl chlorides to produce cis-(dippp)Pd(C6H4X)Cl as the major product and trans-(eta1-dipp)2Pd(C6H4X)Cl as the minor one (X = 4-OMe, 4-Me, H, 3-OMe, 4-COMe, 4-CHO, 4-NO2). In contrast, the dippb complex 1e oxidatively adds chlorobenzene to yield only the trans complex (eta1-dippb)2Pd(Ph)Cl. Reaction monitoring reveals that the cis and trans complexes are formed in parallel pathways. Cis/trans equilibrium is on the cis side for dippp and on the trans side for dippb. Reactivity toward chlorobenzene follows the trend Pd(dippp)2 > Pd(PiPr2nBu)3 >> Pd(dippe)2 >> Pd(dPPP)2. These results are interpreted in terms of chelate stability, ligand basicity, concentration of the active 14e species and effect of the P-Pd-P angle on its reactivity. The dippp ligand is unique in that it is the only one of those studied which results in Pd(0) complexes which (a) exhibit high reactivity in oxidative addition and (b) form cis complexes preferentially.

  DOI：

  10.1021/om00029a025