monophenyl phosphite | 3486-75-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: monophenyl phosphite
• 英文别名: Phenylphosphit；Monophenylphosphit；phenol, phosphite；Phenol-phosphite；phenyl dihydrogen phosphite
• CAS: 3486-75-7
• 化学式: C₆H₇O₃P
• 分子量: 158.094
• InChiKey: VCAFTIGPOYBOIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Method of using rhodium quinonoid catalysts
  申请人：Trenkle C. William

  公开号：US20070123715A1

  公开（公告）日：2007-05-31

  In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed.

  根据发明的某些方面，公开了使用铑对苯二酚催化剂进行硼酸偶联加成的方法。
• Rhodium quinonoid catalysts
  申请人：Sweigart A. Dwight

  公开号：US20070117981A1

  公开（公告）日：2007-05-24

  In accordance with one aspect of the invention a rhodium quinonoid catalyst is disclosed.

  根据发明的某一方面，公开了一种铑醌类催化剂。
• [EN] STEREOSELECTIVE SYNTHESIS OF HIGHLY SUBSTITUTED ENAMIDES<br/>[FR] SYSNTHÈSE STÉRÉOSÉLECTIVE D'ÉNAMIDES À FORTE SUBSTITUTION
  申请人：UNIV NANYANG TECH

  公开号：WO2012173572A1

  公开（公告）日：2012-12-20

  The disclosure provides new methods for the oxidative Heck cross-coupling reaction with electron-rich alkenes such as substituted β-amidoacrylate and other related substituted enamides. Previously, functionalization of enamides under Heck conditions has been limited to those with unsubstituted vinyl groups. By tuning the reaction parameters that allow for the balance between stability and reactivity of the reactants, the oxidative Heck cross-coupling reaction now provides highly substituted enamides in good to excellent yields. (II) (III) (I)·

  披露提供了与富电子烯烃如取代β-酰胺丙烯酸酯以及其他相关取代的亚胺进行氧化Heck交叉偶联反应的新方法。以前，在Heck条件下对亚胺进行官能团化仅限于那些不含取代基的乙烯基团。通过调整反应参数，以平衡反应物的稳定性和活性，氧化Heck交叉偶联反应现在能够以良好到优异的产率提供高度取代的亚胺。
• BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS AND PRODRUGS THEREOF
  申请人：Bristol-Myers Squibb Company

  公开号：US20140087992A1

  公开（公告）日：2014-03-27

  Disclosed are compounds of Formula (I) and/or salts thereof: wherein R 1 is —CH 2 CH 2 CF 3 ; R 2 is —CH 2 CH 2 CF 3 or —CH 2 CH 2 CH 2 CF 3 ; R 3 is H, —CH 3 , or R x ; R 4 is H or R y ; Ring A is phenyl or pyridinyl; and R x , R y , R a , R b , y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer; or as prodrugs of such compounds.

  公开了公式(I)的化合物及/或其盐：其中R1为-CH2CH2CF3；R2为-CH2CH2CF3或-CH2CH2CH2CF3；R3为H，-CH3或Rx；R4为H或Ry；环A为苯基或吡啶基；Rx，Ry，Ra，Rb，y和z在此定义。还公开了使用这些化合物抑制Notch受体的方法，以及包含这些化合物的药物组合物。这些化合物在治疗、预防或减缓多种治疗领域，如癌症的疾病或病症进展方面非常有用，或者作为这些化合物的前药。
• [EN] COMPOUNDS COMPRISING PHOSPHORUS-CONTAINING METAL COMPLEXES<br/>[FR] COMPOSES COMPRENANT DES COMPLEXES METALLIQUES CONTENANT DU PHOSPHORE
  申请人：DU PONT

  公开号：WO2004016710A1

  公开（公告）日：2004-02-26

  Compounds comprising phosphorus-containing metal complexes can be used in electroluminescent devices and have an emission maximum closer to the blue region of the visible light spectrum. The complexes can be used within an organic active layer in electronic devices, such as displays, detectors, voltaic cells, solid-state lighting, illumination devices or the like. The complexes may also be used as catalysts or as indicators in other applications. The new compounds can be used without the need of a host material. In non-limiting embodiments, Pt or Ir may be used for the metal atom within the complex, one ligand may include a phosphorus-containing bidentate ligand, and another ligand may include a monoanionic bidentate ligand. The phosphorus-containing bidentate ligand may include a benzyl group, a phenoxy group, a phenylamino group, or the like.

  含磷金属配合物的化合物可用于电致发光器件，并且其发射峰值更接近可见光谱的蓝色区域。这些配合物可用于电子器件中的有机活性层，如显示器、探测器、伏打电池、固态照明、照明设备等。这些配合物也可用作催化剂或其他应用中的指示剂。这些新化合物可在无需宿主材料的情况下使用。在非限制性实施例中，金属原子可以使用Pt或Ir，一个配体可以包括含磷的双齿配体，另一个配体可以包括单阴离子双齿配体。含磷的双齿配体可以包括苄基、苯氧基、苯胺基等。