3-Furan-2-yl-5-methylamino-2-nitro-biphenyl-4-carboxylic acid ethyl ester | 889128-69-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Furan-2-yl-5-methylamino-2-nitro-biphenyl-4-carboxylic acid ethyl ester
• CAS: 889128-69-2
• 化学式: C₂₀H₁₈N₂O₅
• 分子量: 366.373
• InChiKey: MQXFWLWZLYFMQM-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  3-Furan-2-yl-5-methylamino-2-nitro-biphenyl-4-carboxylic acid ethyl ester 以 水 、 溶剂黄146 为溶剂， 以55%的产率得到3-Furan-2-yl-5-methylamino-2-nitro-biphenyl-4-carboxylic acid
  参考文献：
  名称：

  New synthesis of 3-(2-furyl)biphenyls

  摘要：

  3-(2-Furyl)biphenyls 2a-d were prepared by the rearrangement of 4-(2-furyl)-1,2-dimethyl-5-nitro-6-phenylpyridinium salts under the action of an alkali solution in aqueous ethanol.

  DOI：

  10.1070/mc2006v016n01abeh002204
• 作为产物：
  描述：

  3-ethoxycarbonyl-4-(2-furyl)-1,2-dimethyl-5-nitro-6-phenylpyridin-1-ium perchlorate 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 18.0h， 以11%的产率得到3-Furan-2-yl-5-methylamino-2-nitro-biphenyl-4-carboxylic acid ethyl ester
  参考文献：
  名称：

  New synthesis of 3-(2-furyl)biphenyls

  摘要：

  3-(2-Furyl)biphenyls 2a-d were prepared by the rearrangement of 4-(2-furyl)-1,2-dimethyl-5-nitro-6-phenylpyridinium salts under the action of an alkali solution in aqueous ethanol.

  DOI：

  10.1070/mc2006v016n01abeh002204

文献信息

• Nitropyridines: IV. Synthesis of 3-(2-furyl)biphenyls by recyclization of nitropyridinium salts
  作者：G. P. Sagitullina、L. V. Glizdinskaya、R. S. Sagitullin

  DOI：10.1134/s1070428007040197

  日期：2007.4

  The two-component Hantzsch synthesis using 3-(2-furyl)-2-nitro-1-phenylprop-2-en-1-one and various enamines gave the corresponding nitro-substituted dihydropyridines which were converted into nitropyridines and N-methylpyridinium salts. Recyclization of the latter by the action of aqueous-alcoholic alkali led to the formation of 3-(2-furyl)-2-nitrobiphenyl derivatives.