β-Amino-β-methylbutyrylchlorid | 96279-35-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: β-Amino-β-methylbutyrylchlorid
• 英文别名: 3-Amino-3-methylbuttersaeurechlorid；3-Amino-3-methylbutanoyl chloride
• CAS: 96279-35-5
• 化学式: C₅H₁₀ClNO
• mdl: MFCD19206538
• 分子量: 135.594
• InChiKey: LXEJXTFLNZSUGD-UHFFFAOYSA-N

物化性质

• 沸点：
  170.3±23.0 °C(Predicted)
• 密度：
  1.099±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• FUSED-CYCLIC PYRAZOLONE FORMAMIDE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF
  申请人：Shanghai Institute of Materia Medica, Chinese Academy of Sciences

  公开号：EP3798218A1

  公开（公告）日：2021-03-31

  Provided are a class of fused-cyclic pyrazolone formamide compounds and a preparation method therefor, a pharmaceutical composition and the use thereof. Specifically, provided is a compound having the structure as shown in formula (I) (with each group defined in the description). The compound can be used as an AXL inhibitor in the preparation of a pharmaceutical composition for treating tumors.

  本发明提供了一类融合环状吡唑酮甲酰胺化合物及其制备方法、药物组合物和用途。具体而言，提供了一种具有如式（I）所示结构的化合物（各基团在描述中定义）。该化合物可作为AXL抑制剂用于制备治疗肿瘤的药物组合物。
• ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS
  申请人：Boehringer Ingelheim Animal Health USA Inc.

  公开号：US20200299304A1

  公开（公告）日：2020-09-24

  This invention provides for compounds of the formula: wherein the variables are defined herein, or a stereoisomer, tautomer, N-oxide, hydrate, solvate, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.