benzyl 4,6-O-benzylidene-2-deoxy-3-O-p-methoxybenzyl-2-phthalimido-β-D-glucopyranoside | 934183-60-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: benzyl 4,6-O-benzylidene-2-deoxy-3-O-p-methoxybenzyl-2-phthalimido-β-D-glucopyranoside
• CAS: 934183-60-5
• 化学式: C₃₆H₃₃NO₈
• 分子量: 607.66
• InChiKey: OZNSTPNECUGAJM-BWNORCQLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  45.0
• 可旋转键数：
  9.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  92.76
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  benzyl 4,6-O-benzylidene-2-deoxy-3-O-p-methoxybenzyl-2-phthalimido-β-D-glucopyranoside 在 对甲苯磺酸 作用下， 以 甲醇 、 乙腈 为溶剂， 反应 11.0h， 以78%的产率得到benzyl 2-deoxy-3-O-p-methoxybenzyl-2-phthalimido-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of complex-type glycans derived from parasitic helminths

  摘要：

  Chemical synthesis of complex-type glycans 1 and 2 derived from eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum, is described. These branched sugar chains were synthesized regio- and stereo selectively by using beta-mannosylation, desilylation under high pressure, and glycosylation in frozen solvent as key transformations. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.10.100
• 作为产物：
  描述：

  2,2,2-三氯代亚氨逐乙酸-4-甲氧基苄酯 、 benzyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 在 lanthanum(lll) triflate 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 以79%的产率得到benzyl 4,6-O-benzylidene-2-deoxy-3-O-p-methoxybenzyl-2-phthalimido-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of complex-type glycans derived from parasitic helminths

  摘要：

  Chemical synthesis of complex-type glycans 1 and 2 derived from eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum, is described. These branched sugar chains were synthesized regio- and stereo selectively by using beta-mannosylation, desilylation under high pressure, and glycosylation in frozen solvent as key transformations. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.10.100