N,2-Bis[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazine-1-carboxamide | 106677-40-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N,2-Bis[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazine-1-carboxamide
• 英文别名: 1-[(2-hydroxyphenyl)methylidene]-3-[(2-hydroxyphenyl)methylideneamino]urea
• CAS: 106677-40-1
• 化学式: C₁₅H₁₃N₃O₃
• 分子量: 283.287
• InChiKey: WGGIQAXDRJWHFI-UHFFFAOYSA-N

物化性质

• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  94.3
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  聚合甲醛 、 N,2-Bis[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazine-1-carboxamide 以 二甲基亚砜 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Synthesis, characterization and biocidal activities of Schiff base polychelates containing polyurethane links in the main chain

  摘要：

  The concept of combining metallo-polymers with urethanes offers a versatile approach for the synthesis of new polymeric materials. Polyurethane containing transition metals was synthesized by the reaction of Schiff base metal complex with toluene 2,4 diisocyanate. The proposed structures were confirmed by elemental analysis, H-1 NMR, C-13 NMR and FT-IR. The geometry is determined by UV-Visible spectra and magnetic moment measurements, which reveals that the Mn(II), Co(II) and Ni(II) complexes have octahedral geometry while square planer geometry is reported for Cu(II) and tetrahedral for Zn(II) complex. The antimicrobial activities are determined using the agar well diffusion method with Staphylococcus aureus, Escherichia coli, Bacillus subtilis (bacteria), Aspergillus niger, Candida albicans and Aspergillus flavus (yeast). All the polymeric metal complexes show comparatively good biocidal activity, which is further enhanced after polymerization. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2012.04.018
• 作为产物：
  描述：

  水杨醛 、 S-(4-叔-丁基苯甲基)[2-(1-甲基丁基)吡啶-3-基]硫代氨基甲酸酯 以 乙醇 、 水 为溶剂， 反应 2.0h， 以76.2%的产率得到N,2-Bis[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazine-1-carboxamide
  参考文献：
  名称：

  Synthesis, characterization and biocidal activities of Schiff base polychelates containing polyurethane links in the main chain

  摘要：

  The concept of combining metallo-polymers with urethanes offers a versatile approach for the synthesis of new polymeric materials. Polyurethane containing transition metals was synthesized by the reaction of Schiff base metal complex with toluene 2,4 diisocyanate. The proposed structures were confirmed by elemental analysis, H-1 NMR, C-13 NMR and FT-IR. The geometry is determined by UV-Visible spectra and magnetic moment measurements, which reveals that the Mn(II), Co(II) and Ni(II) complexes have octahedral geometry while square planer geometry is reported for Cu(II) and tetrahedral for Zn(II) complex. The antimicrobial activities are determined using the agar well diffusion method with Staphylococcus aureus, Escherichia coli, Bacillus subtilis (bacteria), Aspergillus niger, Candida albicans and Aspergillus flavus (yeast). All the polymeric metal complexes show comparatively good biocidal activity, which is further enhanced after polymerization. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2012.04.018