4-amino-1-isobutyl-1H-pyrimidin-2-one | 25855-41-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-amino-1-isobutyl-1H-pyrimidin-2-one
• 英文别名: 4-Amino-1-(2-methylpropyl)pyrimidin-2-one
• CAS: 25855-41-8
• 化学式: C₈H₁₃N₃O
• 分子量: 167.211
• InChiKey: UJMRWNQBSFNFSY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  58.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] METHODS OF TREATING VIRAL ASSOCIATED DISEASES<br/>[FR] PROCÉDÉS DE TRAITEMENT DE MALADIES ASSOCIÉES À DES VIRUS
  申请人：CHIMERIX INC

  公开号：WO2011053812A1

  公开（公告）日：2011-05-05

  The present invention provides methods of treating diseases associated with at least one virus. The methods include administering a compound described in the invention in a therapeutically effective amount. According to some aspects of the present invention, the methods may further comprise at least one immunosuppressant agent to treat diseases associated with at least one virus of a subject in need of immunosuppressant agents.