| 951225-20-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• CAS: 951225-20-0
• 化学式: C₅₅H₄₉N₅O₂₀
• 分子量: 1100.02
• InChiKey: ZYIJJEVKGAJZFP-KBWIYFJQSA-N

反应信息

• 作为反应物：
  描述：

  在 potassium chloride 作用下， 生成
  参考文献：
  名称：

  Photoactivatable and Water Soluble FRET Dyes with High Uncaging Cross Section

  摘要：

  Photoactivatable fluorophores are powerful imaging probes for tracking molecular and cellular dynamics with high spatiotemporal resolution. We have designed and synthesized a new caged FREr dye, CCC-1, comprising a caged cournarin and a water soluble xanthene dye. CCC-1 can be efficiently photolyzed by ultraviolet light. Its photolyzed product, CC-1, emits strong green fluorescence with a FREr efficiency of 95% when excited near 410 nm. The uncaging cross section of CCC-1 is about 6000 M-1cm-1 at 365 nm, more than a hundred times higher than caged fluoresceins developed previously. The probe is also blocompatible and has built-in functionalities for bioconjugation.

  DOI：

  10.1021/ja071427+
• 作为产物：
  描述：

  在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 生成
  参考文献：
  名称：

  Photoactivatable and Water Soluble FRET Dyes with High Uncaging Cross Section

  摘要：

  Photoactivatable fluorophores are powerful imaging probes for tracking molecular and cellular dynamics with high spatiotemporal resolution. We have designed and synthesized a new caged FREr dye, CCC-1, comprising a caged cournarin and a water soluble xanthene dye. CCC-1 can be efficiently photolyzed by ultraviolet light. Its photolyzed product, CC-1, emits strong green fluorescence with a FREr efficiency of 95% when excited near 410 nm. The uncaging cross section of CCC-1 is about 6000 M-1cm-1 at 365 nm, more than a hundred times higher than caged fluoresceins developed previously. The probe is also blocompatible and has built-in functionalities for bioconjugation.

  DOI：

  10.1021/ja071427+