(S)-2-(dibenzylamino)propyl 4-(2-(1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)ethyl)piperidine-1-carboxylate | 1089274-90-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: (S)-2-(dibenzylamino)propyl 4-(2-(1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)ethyl)piperidine-1-carboxylate
• 英文别名: [(2S)-2-(dibenzylamino)propyl] 4-[2-(2-oxo-3H-benzimidazol-1-yl)ethyl]piperidine-1-carboxylate
• CAS: 1089274-90-7
• 化学式: C₃₂H₃₈N₄O₃
• 分子量: 526.679
• InChiKey: HAIYHAIRCNFFOR-VWLOTQADSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  39
• 可旋转键数：
  11
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  65.1
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
  申请人：Commissariat à l'Energie Atomique

  公开号：EP1997805A1

  公开（公告）日：2008-12-03

  The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.

  这项发明涉及具有抗寄生虫活性的化合物，以及它们作为药物的用途，特别是作为预防和/或治疗由顶复合体寄生虫引起的寄生虫病的药物。该发明还涉及含有这些化合物的药物组合物。
• Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans
  申请人：Deligny Michael

  公开号：US20100292214A1

  公开（公告）日：2010-11-18

  The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.

  本发明涉及具有抗寄生活性的化合物及其作为药物的使用，特别是用于预防和/或治疗由顶复门寄生虫引起的寄生虫病。本发明还涉及含有这些化合物的制药组合物。