Sodium;gadolinium(3+);tetrafluoride | 15640-94-5

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 镧系盐
• 英文名称: Sodium;gadolinium(3+);tetrafluoride
• CAS: 15640-94-5
• 化学式: F₄Gd*Na
• 分子量: 256.233
• InChiKey: OWFHVHWXOGAVRB-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  -14.98
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  NaGd(trifluoroacetate)₄(diglyme) 生成 Sodium;gadolinium(3+);tetrafluoride
  参考文献：
  名称：

  从单一来源的前体直接合成六角形的NaGdF4纳米晶体：将NaGdF4：Yb3 +，Tm3 +及其与TiO2的复合物上转换用于近红外驱动的光催化

  摘要：

  合成了新颖的单源前驱体NaGd（TFA）4（二甘醇二甲醚）（TFA =三氟乙酸盐），并进行了表征，并用于获得NaGdF 4纳米颗粒的六方相，作为镧系元素掺杂的上转换纳米晶体（NC）的有效基质将近红外辐射转换为波长较短的紫外线/可见光。然后将这些NC用于制备性能良好的TiO 2 @NaGdF 4：Yb 3+，Tm 3+纳米复合材料，从而将TiO 2光催化剂的吸收范围从UV扩展到IR区。虽然光致发光光谱的可见/近红外部分几乎不受TiO 2的存在的影响由于能量转移或FRET ，TiO 2在其缝隙上方约380 nm处被吸收，因此UV部分被强烈淬灭。给出了以上获得的纳米复合材料的光催化活性的初步结果。

  DOI：

  10.1002/asia.201402347

文献信息

• Mechanochemical Synthesis of Nano-sized Complex Fluorides from Pair of Different Constituent Fluoride Compounds
  作者：Jinfeng Lu、Qiwu Zhang、Fumio Saito

  DOI：10.1246/cl.2002.1176

  日期：2002.12

  Complex fluorides ARF4 (A = Li, Na, K, R = rare earthes) are synthesized by the mechanochemical solid reactions of AF and RF3 powders at room temperature using a planetary ball mill. The reactions proceed with the increase of grinding time and have been completed at 4 h. Transmission electron microscope observation shows that the produced ARF4 powders consist of agglomerates of nano-sized primary particles, which exhibit moderate water solubility. When the ground sample is calcined, the particle size is increased and the water solubility is depressed.

  复合氟化物ARF4（A = Li、Na、K，R = 稀土）是通过AF和RF3粉末在室温下使用行星球磨机进行机械化学固体反应合成的。反应随着研磨时间的增加而进行，并在4小时后完成。透射电子显微镜观察显示，产生的ARF4粉末由纳米级初级颗粒的团聚体组成，表现出中等的水溶性。当研磨的样品被煅烧时，粒径增加，水溶性降低。
• Stable gadolinium based nanoscale lyophilized injection for enhanced MR angiography with efficient renal clearance
  作者：Kun Liu、Liang Dong、Yunjun Xu、Xu Yan、Fei Li、Yang Lu、Wei Tao、Huangyong Peng、Yadong Wu、Yang Su、Daishun Ling、Tao He、Haisheng Qian、Shu-Hong Yu

  DOI：10.1016/j.biomaterials.2017.12.023

  日期：2018.3

  There is a great demand to develop high-relaxivity nanoscale contrast agents for magnetic resonance (MR) angiography with high resolution. However, there should be more focus on stability, ion leakage and excretion pathway of the intravenously injected nanoparticles, which are closely related to their clinic potentials. Herein, uniform ultrasmall-sized NaGdF4 nanocrystal (sub-10 nm) was synthesized using a facile high temperature organic solution method, and the nanocrystals were modified by a ligand-exchange approach using PEG-PM di-block copolymer. The PEG-PAA modified NaGdF4 nano crystal (denoted as ppNaGdF(4) nanocrystal) exhibited a high r(1) relaxivity which was twice of commercially used gadopentetate dimeglumine (Gd-DTPA) injection. MR angiography on rabbit using ppNaGdF(4) nanocrystal at a low dose showed enhanced vascular details and long circulation time. Lyophilized powder of ppNaGdF(4) nanocrystals have been successfully prepared without aggregation or reduction of MR performance, indicating the stability and an effective way to store this nanoscale contrast agent. No haemolysis was induced by ppNaGdF(4) nanocrystal, and an extremely low leakage of gadolinium ions was confirmed. Furthermore, efficient renal excretion was one of the clearance pathways of ppNaGdF(4) nanocrystal according to both the time dependent distribution data in blood and tissues and MR images. The in vivo toxicity evaluation further validated the great potential as a clinical agent for blood pool imaging. (C) 2018 Elsevier Ltd. All rights reserved.
• Coprecipitation from aqueous solutions to prepare binary fluorides
  作者：P. P. Fedorov、S. V. Kuznetsov、M. N. Mayakova、V. V. Voronov、R. P. Ermakov、A. E. Baranchikov、V. V. Osiko

  DOI：10.1134/s003602361110007x

  日期：2011.10

  The synthesis of binary fluoride phases, specifically nanofluorides, by coprecipitation from aqueous solutions is considered in terms of phase equilibria. Phases have been precipitated in NaF-RF3 systems (where R stands for a rare-earth element), MF2-YF3 systems (where M = Ca, Sr, Ba), BaF2-ScF3, and CaF2-BaF2 systems. In the MF2-YF3 systems, unordered metastable congruently soluble phases are precipitated instead of ordered fluorite-like phases. In the BaF2-ScF3 system, the congruently soluble compound Ba3Sc2F12 is precipitated. In the NaF-RF3 systems, incongruently soluble metastable phases with a fluorite-like structure (for R = Er, Lu, Y) and the gagarinite structure (NaGdF4) are formed. In the CaF2-BaF2 system, intermediate phases have not been formed.
• Direct Synthesis of Hexagonal NaGdF₄Nanocrystals from a Single-Source Precursor: Upconverting NaGdF₄:Yb³⁺,Tm³⁺and Its Composites with TiO₂for Near-IR-Driven Photocatalysis
  作者：Ying Chen、Shashank Mishra、Gilles Ledoux、Erwann Jeanneau、Marlene Daniel、Jinlong Zhang、Stéphane Daniele

  DOI：10.1002/asia.201402347

  日期：2014.9

  single‐source precursor NaGd(TFA)4(diglyme) (TFA=trifluoroacetate) was synthesized, characterized thoroughly, and used to obtain the hexagonal phase of NaGdF4 nanoparticles as an efficient matrix for lanthanide‐doped upconverting nanocrystals (NCs) that convert near‐infrared radiation into shorter‐wavelength UV/visible light. These NCs were then used to prepare well‐characterized TiO2@NaGdF4:Yb3+,Tm3+ nanocomposites

  合成了新颖的单源前驱体NaGd（TFA）4（二甘醇二甲醚）（TFA =三氟乙酸盐），并进行了表征，并用于获得NaGdF 4纳米颗粒的六方相，作为镧系元素掺杂的上转换纳米晶体（NC）的有效基质将近红外辐射转换为波长较短的紫外线/可见光。然后将这些NC用于制备性能良好的TiO 2 @NaGdF 4：Yb 3+，Tm 3+纳米复合材料，从而将TiO 2光催化剂的吸收范围从UV扩展到IR区。虽然光致发光光谱的可见/近红外部分几乎不受TiO 2的存在的影响由于能量转移或FRET ，TiO 2在其缝隙上方约380 nm处被吸收，因此UV部分被强烈淬灭。给出了以上获得的纳米复合材料的光催化活性的初步结果。