6-Chloro-1-p-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | 80751-82-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: 6-Chloro-1-p-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
• 英文别名: 9-chloro-5-(4-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
• CAS: 80751-82-2
• 化学式: C₁₇H₁₈ClNO₂
• 分子量: 303.788
• InChiKey: HUYKVHJHQMMMOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  52.5
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• FENOLDOPAM FORMULATIONS AND PRO-DRUG DERIVATIVES
  申请人：Levite Mia

  公开号：US20110104287A1

  公开（公告）日：2011-05-05

  Formulations of fenoldopam are disclosed for repeated administration or continued slow release administration, over prolonged periods of time or targeted slow and regulated delivery. The formulations include those formulations that increase the bioavailability of fenoldopam after oral intake, particularly lipid based nano dispersions and pronanodispersions and surfactant rich formulations. This may be accomplished by entrapment in nanoparticles or liposomal formulations or conjugation to a polymer or small molecule via a soft bond.
• US8859001B2
  申请人：——

  公开号：US8859001B2

  公开（公告）日：2014-10-14