[(E)-5-hydroxy-4-methylpent-2-enyl] benzoate | 1001068-34-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(E)-5-hydroxy-4-methylpent-2-enyl] benzoate
• CAS: 1001068-34-3
• 化学式: C₁₃H₁₆O₃
• 分子量: 220.268
• InChiKey: KIZBLVMYFQQESZ-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-甲基-3-丁烯-1-醇 、 cis-1,4-dibenzoyloxybut-2-ene 在 Cl₂(1,3-dimesitylimidazolidin-2-yl)Ru=CH(5-NO₂-2-iPrO)C₆H₃ 吡啶 、 三氟乙酸 作用下， 以 二氯甲烷 、 1,2-二氯乙烷 为溶剂， 反应 47.0h， 生成 [(E)-5-hydroxy-4-methylpent-2-enyl] benzoate
  参考文献：
  名称：

  Solid-Phase Olefin Cross-Metathesis Promoted by a Linker

  摘要：

  Olefin cross-metathesis couples two alkenes to form complex molecules and has been widely used in solution-phase organic synthesis. However, this powerful method has rarely been used in solid-phase organic synthesis. Herein we report that olefin cross-metathesis is a synthetically viable method particularly when a traceless longer linker is inserted between solid support and reacting olefins.

  DOI：

  10.1021/ol702415x

文献信息

• Solid-Phase Olefin Cross-Metathesis Promoted by a Linker
  作者：Amanda L. Garner、Kazunori Koide

  DOI：10.1021/ol702415x

  日期：2007.12.1

  Olefin cross-metathesis couples two alkenes to form complex molecules and has been widely used in solution-phase organic synthesis. However, this powerful method has rarely been used in solid-phase organic synthesis. Herein we report that olefin cross-metathesis is a synthetically viable method particularly when a traceless longer linker is inserted between solid support and reacting olefins.