1,1,3,3,5,5-hexakis[2-[2-(2-tetrahydropyranyloxy)ethoxy]ethoxy]cyclotriphosphazene | 155063-86-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 1,1,3,3,5,5-hexakis[2-[2-(2-tetrahydropyranyloxy)ethoxy]ethoxy]cyclotriphosphazene
• 英文别名: 2,2,4,4,6,6-Hexakis[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]-1-aza-3,5-diazanida-2lambda5-phospha-4,6-diphosphoniacyclohexene；2,2,4,4,6,6-hexakis[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]-1-aza-3,5-diazanida-2λ5-phospha-4,6-diphosphoniacyclohexene
• CAS: 155063-86-8
• 化学式: C₅₄H₁₀₂N₃O₂₄P₃
• 分子量: 1270.33
• InChiKey: RYNLIQMKFSFHJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  84
• 可旋转键数：
  48
• 环数：
  7.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  236
• 氢给体数：
  0
• 氢受体数：
  27

反应信息

• 作为反应物：
  描述：

  1,1,3,3,5,5-hexakis[2-[2-(2-tetrahydropyranyloxy)ethoxy]ethoxy]cyclotriphosphazene 在 乙醇 、 4-甲基苯磺酸吡啶 作用下， 反应 24.0h， 以33.1%的产率得到1,1,3,3,5,5-hexakis[2-[2-hydroxyethoxy]ethoxy]cyclotriphosphazene
  参考文献：
  名称：

  Synthesis and Characterization of Brush-Shaped Hybrid Inorganic/Organic Polymers Based on Polyphosphazenes

  摘要：

  A series of densely grafted star- and comb-shaped molecular brushes composed of polystyrene, poly(tertbutyl acrylate), and poly(N-iscopropylacrylamide) were prepared by atom transfer radical polymerization (ATRP) using either cyclotriphosphazenes or polyphosphazenes as initiators. The initiators were prepared by the introduction of a free hydroxyl group into the side chains of a phosphazene cyclic trimer and polymer, followed by esterification with 2-bromopropionyl bromide. The grafting conditions were optimized for various monomers. The kinetics of the reaction were first order with respect to the monomer concentration in both cyclotriphosphazene and polyphosphazene systems. The molecular weights of the resulting polmers were estimated by gel permeation chromatography (GPC). The side chains of the brush polymers were cleaved from the backbone and analyzed by GPC to confirm the synthesis Of well defined polymer brushes. Brushes based on poly(tert-butyl acrylate) were subjected to hydrolysis to yield negatively charged brushes. In addition, the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide) brush polymers was measured by both dynamic light scattering (DLS) and differential scanning calorimetry (DSC), exhibiting a sharp phase transition at 33 degrees C. Furthermore, star- and comb block copolymers with a hard polystyrene core and a soft poly(tert-butyl acrylate) shell were also synthesized.

  DOI：

  10.1021/ma202587z
• 作为产物：
  描述：

  四氢吡喃醚-二聚乙二醇 在 sodium hydride 、 六氯环三磷腈 、 碳酸氢钠 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 48.0h， 以84.9%的产率得到1,1,3,3,5,5-hexakis[2-[2-(2-tetrahydropyranyloxy)ethoxy]ethoxy]cyclotriphosphazene
  参考文献：
  名称：

  Synthesis and Characterization of Brush-Shaped Hybrid Inorganic/Organic Polymers Based on Polyphosphazenes

  摘要：

  A series of densely grafted star- and comb-shaped molecular brushes composed of polystyrene, poly(tertbutyl acrylate), and poly(N-iscopropylacrylamide) were prepared by atom transfer radical polymerization (ATRP) using either cyclotriphosphazenes or polyphosphazenes as initiators. The initiators were prepared by the introduction of a free hydroxyl group into the side chains of a phosphazene cyclic trimer and polymer, followed by esterification with 2-bromopropionyl bromide. The grafting conditions were optimized for various monomers. The kinetics of the reaction were first order with respect to the monomer concentration in both cyclotriphosphazene and polyphosphazene systems. The molecular weights of the resulting polmers were estimated by gel permeation chromatography (GPC). The side chains of the brush polymers were cleaved from the backbone and analyzed by GPC to confirm the synthesis Of well defined polymer brushes. Brushes based on poly(tert-butyl acrylate) were subjected to hydrolysis to yield negatively charged brushes. In addition, the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide) brush polymers was measured by both dynamic light scattering (DLS) and differential scanning calorimetry (DSC), exhibiting a sharp phase transition at 33 degrees C. Furthermore, star- and comb block copolymers with a hard polystyrene core and a soft poly(tert-butyl acrylate) shell were also synthesized.

  DOI：

  10.1021/ma202587z